Protein: MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6 (EC 3.1.3.95) (Myotubularin-related protein 6) (Phosphatidylinositol-3-phosphate phosphatase)

Gene: MTMR6
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q9Y217

Gene Ontology (top 5):
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1400893

MTMR9
Myotubularin-related protein 9

10

16

Small-scale

0.981

High

1490429

MTMR7
Phosphatidylinositol-3-phosphate phosphatase MTMR7

4

18

High-throughput

0.892

High

138889

STK25
Serine/threonine-protein kinase 25

3

5

High-throughput

0.667

High

1328700

KCD17
BTB/POZ domain-containing protein KCTD17

3

5

High-throughput

0.667

High

329999

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

4

0

High-throughput

0.664

High

733863

CDD
Cytidine deaminase

3

1

High-throughput

0.662

High

1490432

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

18

High-throughput

0.618

High

1372454

BHMT1
Betaine--homocysteine S-methyltransferase 1

2

0

High-throughput

0.602

High

347422

BAG2
BAG family molecular chaperone regulator 2

2

1

High-throughput

0.601

High

890277

FHIT
Bis(5'-adenosyl)-triphosphatase

2

0

High-throughput

0.585

High

569597

CATE
Cathepsin E

2

1

High-throughput

0.574

High

572284

TRI27
Zinc finger protein RFP

1

2

High-throughput

0.573

High

1101249

NMI
N-myc-interactor

1

1

High-throughput

0.573

High

1206034

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

3

High-throughput

0.573

High

1490433

AMOL2
Angiomotin-like protein 2

1

3

High-throughput

0.573

High

565541

RARG
Retinoic acid receptor gamma

1

2

High-throughput

0.541

High

1101797

PTK7
Inactive tyrosine-protein kinase 7

1

14

High-throughput

0.541

High

1145796

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

15

High-throughput

0.541

High

1251982

LMTK1
Serine/threonine-protein kinase LMTK1

1

19

High-throughput

0.541

High

1310886

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.541

High

931165

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

1340481

DDX55
ATP-dependent RNA helicase DDX55

1

2

High-throughput

0.536

High

1446144

M1IP1
Mid1-interacting protein 1

1

1

High-throughput

0.536

High

884490

PCY1A
Choline-phosphate cytidylyltransferase A

1

0

High-throughput

0.513

High

1337526

DDHD1
Phospholipase DDHD1

1

0

High-throughput

0.513

High

1453959

RN181
E3 ubiquitin-protein ligase RNF181

1

0

High-throughput

0.513

High

641707

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

19

High-throughput

0.494

High

1034382

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

19

High-throughput

0.494

High

389900

TTHY
Transthyretin

1

1

High-throughput

0.489

High

1200345

ANR39
Ankyrin repeat domain-containing protein 39

1

1

High-throughput

0.489

High

1384233

LDAF1
Lipid droplet assembly factor 1

1

1

High-throughput

0.489

High

1452177

ALKB4
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

1

0

Small-scale

0.486

High

243313

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

364048

EGFR
Epidermal growth factor receptor

1

15

High-throughput

0.479

High

390817

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

533076

CH60
60 kDa heat shock protein, mitochondrial

1

6

High-throughput

0.479

High

541762

FGFR1
Fibroblast growth factor receptor 1

1

16

High-throughput

0.479

High

630667

RAB3B
Ras-related protein Rab-3B

1

3

High-throughput

0.479

High

631026

RAB4A
Ras-related protein Rab-4A

1

3

High-throughput

0.479

High

631568

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.479

High

641286

FGFR2
Fibroblast growth factor receptor 2

1

17

High-throughput

0.479

High

648746

FGFR4
Fibroblast growth factor receptor 4

1

16

High-throughput

0.479

High

774013

SOAT1
Sterol O-acyltransferase 1

1

3

High-throughput

0.479

High

899633

TCPD
T-complex protein 1 subunit delta

1

4

High-throughput

0.479

High

902147

RAB9A
Ras-related protein Rab-9A

1

8

High-throughput

0.479

High

953191

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

976673

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

1031603

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.479

High

1211038

CE170
Centrosomal protein of 170 kDa

1

1

High-throughput

0.479

High

1229141

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.479

High

1256136

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1293436

CARM1
Histone-arginine methyltransferase CARM1

1

1

High-throughput

0.479

High

1350504

BICD2
Protein bicaudal D homolog 2

1

4

High-throughput

0.479

High

1361940

TITIN
Titin

1

3

High-throughput

0.479

High

1363716

TCPW
T-complex protein 1 subunit zeta-2

1

5

High-throughput

0.479

High

1386635

OPTN
Optineurin

1

5

High-throughput

0.479

High

1429020

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

1458936

ZO2
Tight junction protein 2

1

6

High-throughput

0.479

High

1459890

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

1369805

RAD50
DNA repair protein RAD50

1

2

High-throughput

0.470

High

189935

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

226270

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

561160

GILT
Gamma-interferon-inducible lysosomal thiol reductase

1

0

High-throughput

0.458

High

880405

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.458

High

904416

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

927615

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

1128869

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1149398

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1311540

BBS7
BBSome complex member BBS7

1

0

High-throughput

0.458

High

1397129

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1445848

S40A1
Ferroportin

1

0

High-throughput

0.458

High

766023

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

140034

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

218971

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

327505

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

560560

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.437

High

590054

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

696887

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

769536

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1276375

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

1103886

PM2P3
Putative postmeiotic segregation increased 2-like protein 3

1

2

High-throughput

0.407

High

1239073

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.407

High

873887

KCNJ5
G protein-activated inward rectifier potassium channel 4

2

0

High-throughput

0.328

High

967284

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

1451229

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.279

Low

880987

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

1233584

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1293211

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

832838

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.232

Low

1251208

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025