HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 2610
+	Hs
		197105 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		903601 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1288384 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1281471 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1357021 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1032165 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		125431 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		304102 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304289 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		125310 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		1032091 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Sc
		765276 EIF3I_YEAST (141-325): 9.4e-30: 117: 13.36		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86
+	Hs
		125811 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Ce
		1281030 EIF3I_CAEEL (141-325): 1e-23: 100: 13.72		Q9GUP2_CAEEL (2359-2608): 2.04e-79: 297: 29.57
+	Hs
		1056609 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		903156 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95