HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: WIPI2 (Q9Y4P8)
WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)
Gene: WIPI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 454
+	Sp
		999842 TUP12_SCHPO (4-220): 2.53e-65: 217: 20.89		TUP11_SCHPO (138-432): 1.03e-55: 196: 15.76
+	Hs
		1240486 POC1A_HUMAN (81-324): 1.17e-56: 190: 14.63		WIPI4_HUMAN (33-367): 8.32e-64: 211: 21.81
+	Hs
		1240442 POC1A_HUMAN (81-324): 1.17e-56: 190: 14.63		POC1B_HUMAN (198-434): 1.58e-46: 169: 13.04
+	Hs
		929440 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		RACK1_HUMAN (177-426): 2.51e-14: 75.6: 16.54
+	Hs
		903197 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		WDR5_HUMAN (319-430): 3.33e-10: 63: 12.80
+	Sp
		999838 TUP11_SCHPO (171-324): 1.02e-32: 129: 17.39		TUP11_SCHPO (138-432): 1.03e-55: 196: 15.76
+	Hs
		792949 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		LIS1_HUMAN (3-233): 1.6e-51: 180: 10.55
+	Hs
		903418 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		FBXW7_HUMAN (140-429): 1.13e-45: 170: 9.12
+	Sc
		630844 NLE1_YEAST (2-125): 1.27e-34: 133: 21.43		NLE1_YEAST (147-447): 6.18e-44: 162: 14.87
+	Sc
		744629 EIF3I_YEAST (141-325): 9.4e-30: 117: 13.36		TAF5_YEAST (147-414): 2.2e-35: 141: 13.70
+	Hs
		903349 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WDR5B_HUMAN (283-446): 4.78e-20: 92.7: 9.44
+	Hs
		196984 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		WDR5_HUMAN (319-430): 3.33e-10: 63: 12.80
+	Hs
		903109 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		RACK1_HUMAN (177-426): 2.51e-14: 75.6: 16.54
+	Hs
		903077 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WDR5_HUMAN (319-430): 3.33e-10: 63: 12.80
+	Hs
		903502 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		SKI8_HUMAN (22-233): 3.35e-10: 62.9: 13.83
+	Hs
		903551 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		NLE1_HUMAN (326-431): 8.49e-09: 59.6: 8.80
+	Dm
		1358845 WDS_DROME (177-325): 5.55e-38: 140: 16.67		WDS_DROME (319-430): 4.34e-09: 59.9: 8.80
+	Hs
		903428 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		WDR5_HUMAN (319-430): 3.33e-10: 63: 12.80