HitPredict

Interactor 1: PPIG (Q13427)
Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G)
Gene: PPIG

Interactor 2: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.831

Property	Details
Experiments	25416956, 35271311
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Pro_isomerase~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 754 Hs			1 530
+	Hs
		203522 PPIH_HUMAN (5-177): 3.52e-98: 302: 52.02		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		614322 PPIB_HUMAN (4-188): 7.54e-97: 300: 49.74		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		673795 NKTR_HUMAN (7-385): 7.16e-67: 243: 52.67		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00