HitPredict

Interactor 1: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Interactor 2: KBTB8 (Q8NFY9)
Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP)
Gene: KBTBD8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.688

Property	Details
Experiments	26399832, 29999490, 30190310
Identification Methods	affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006417 - regulation of translation GO:0014029 - neural crest formation GO:0014032 - neural crest cell development
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1488 Hs			1 601
+	Hs
		1201309 MAGE1_HUMAN (181-639): 6.02e-12: 72.9: 10.37		KBTB6_HUMAN (11-598): 3.2e-159: 473: 27.39
+	Hs
		1057032 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		KLH20_HUMAN (250-440): 5.47e-24: 108: 16.23
+	Dm
		54891 A1ZA72_DROME (61-1471): 1e-17: 92.5: 15.45		Q9VK21_DROME (483-593): 6.47e-10: 64.1: 14.29