Protein: PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-4) (Phospholipase C-beta-4) (PLC-beta-4)

Gene: PLCB4
Organism: Homo sapiens
Interactions: 35
UniProt ID: Q15147

Gene Ontology (top 5):
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0004629 - phospholipase C activity
GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

126607

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

466263

RHOC
Rho-related GTP-binding protein RhoC

1

15

High-throughput

0.618

High

581061

RAC2
Ras-related C3 botulinum toxin substrate 2

1

13

High-throughput

0.618

High

601297

RHOQ
Rho-related GTP-binding protein RhoQ

1

17

High-throughput

0.618

High

944996

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.618

High

953459

RAC3
Ras-related C3 botulinum toxin substrate 3

1

14

High-throughput

0.618

High

955188

CDC42
Cell division control protein 42 homolog

1

15

High-throughput

0.618

High

962068

RHOA
Transforming protein RhoA

1

16

High-throughput

0.618

High

976279

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.618

High

978018

RHOB
Rho-related GTP-binding protein RhoB

1

17

High-throughput

0.618

High

988379

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.618

High

1015452

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.618

High

1143116

RHOH
Rho-related GTP-binding protein RhoH

1

17

High-throughput

0.618

High

1143120

RHOV
Rho-related GTP-binding protein RhoV

1

15

High-throughput

0.618

High

1143122

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.618

High

1143123

RHOF
Rho-related GTP-binding protein RhoF

1

19

High-throughput

0.618

High

1048858

REL
Proto-oncogene c-Rel

1

2

High-throughput

0.573

High

1143125

NLGN3
Neuroligin-3

1

0

Small-scale

0.486

High

413869

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

535085

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.479

High

692973

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

1051664

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

3

Small-scale

0.479

High

1143119

PDC6I
Programmed cell death 6-interacting protein

1

2

High-throughput

0.479

High

1143117

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.470

High

402772

CYTB
Cystatin-B

1

0

High-throughput

0.458

High

974749

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.458

High

1141445

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

0

High-throughput

0.458

High

1143118

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1143121

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1143124

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

0

High-throughput

0.458

High

255029

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

529829

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

893871

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.439

High

1132705

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.437

High

246612

KDM1A
Lysine-specific histone demethylase 1A

1

0

Small-scale

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025