Protein: I12R1
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)

Gene: I12R1, IL12RB1
Organism: Homo sapiens
Interactions: 78
UniProt ID: P42701

Gene Ontology (top 5):
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002230 - positive regulation of defense response to virus by host
GO:0002827 - positive regulation of T-helper 1 type immune response
GO:0004896 - cytokine receptor activity
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

667344

IL12B
Interleukin-12 subunit beta

2

17

Small-scale

0.754

High

789635

CREL2
Protein disulfide isomerase CRELD2

2

5

High-throughput

0.705

High

488151

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

3

High-throughput

0.691

High

574507

ITB5
Integrin beta-5

1

8

High-throughput

0.691

High

789619

SEM3B
Semaphorin-3B

1

2

High-throughput

0.691

High

789642

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

2

High-throughput

0.691

High

789659

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

2

High-throughput

0.691

High

789664

JAG2
Protein jagged-2

1

5

High-throughput

0.691

High

789665

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.691

High

501794

BIP
Endoplasmic reticulum chaperone BiP

3

5

High-throughput

0.667

High

667325

IL12A
Interleukin-12 subunit alpha

2

1

Small-scale

0.624

High

789613

LAMB2
Laminin subunit beta-2

1

13

High-throughput

0.618

High

789633

POTEE
POTE ankyrin domain family member E

1

1

High-throughput

0.618

High

789656

LTBP3
Latent-transforming growth factor beta-binding protein 3

1

1

High-throughput

0.618

High

789655

IL23A
Interleukin-23 subunit alpha

1

0

Small-scale

0.614

High

789636

TBA1A
Tubulin alpha-1A chain

2

6

High-throughput

0.611

High

381143

TBB4A
Tubulin beta-4A chain

3

8

High-throughput

0.609

High

789617

TBA4A
Tubulin alpha-4A chain

3

6

High-throughput

0.609

High

789622

TBB3
Tubulin beta-3 chain

3

8

High-throughput

0.609

High

789629

TBB8
Tubulin beta-8 chain

3

8

High-throughput

0.609

High

789648

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

3

1

High-throughput

0.609

High

789652

TXNIP
Thioredoxin-interacting protein

3

5

High-throughput

0.609

High

528723

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

789634

CSPG4
Chondroitin sulfate proteoglycan 4

1

2

High-throughput

0.536

High

789643

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

1

High-throughput

0.536

High

789645

NEUR1
Sialidase-1

1

2

High-throughput

0.536

High

789663

NEUR3
Sialidase-3

1

2

High-throughput

0.536

High

789630

IL23R
Interleukin-23 receptor

1

18

Small-scale

0.534

High

789638

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.513

High

789646

TM9S2
Transmembrane 9 superfamily member 2

1

0

High-throughput

0.513

High

789657

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.513

High

172739

ZN185
Zinc finger protein 185

1

1

High-throughput

0.489

High

302376

CSTN1
Calsyntenin-1

1

20

High-throughput

0.489

High

313126

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

1

1

High-throughput

0.489

High

428072

TBB5
Tubulin beta chain

1

8

High-throughput

0.489

High

518278

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

653183

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.489

High

789611

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.489

High

789618

TBB4B
Tubulin beta-4B chain

1

8

High-throughput

0.489

High

789620

DNJC3
DnaJ homolog subfamily C member 3

1

4

High-throughput

0.489

High

789621

OS9
Protein OS-9

1

1

High-throughput

0.489

High

789623

TBB2A
Tubulin beta-2A chain

1

8

High-throughput

0.489

High

789624

GANAB
Neutral alpha-glucosidase AB

1

3

High-throughput

0.489

High

789625

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

1

High-throughput

0.489

High

789626

DPOD3
DNA polymerase delta subunit 3

1

3

High-throughput

0.489

High

789628

NPTX1
Neuronal pentraxin-1

1

1

High-throughput

0.489

High

789631

ACD10
Acyl-CoA dehydrogenase family member 10

1

4

High-throughput

0.489

High

789637

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

1

High-throughput

0.489

High

789641

VWDE
von Willebrand factor D and EGF domain-containing protein

1

6

High-throughput

0.489

High

789647

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.489

High

789649

TBB6
Tubulin beta-6 chain

1

8

High-throughput

0.489

High

789653

TBB1
Tubulin beta-1 chain

1

9

High-throughput

0.489

High

789654

ESRP2
Epithelial splicing regulatory protein 2

1

5

High-throughput

0.489

High

789658

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.489

High

789660

FBX2
F-box only protein 2

1

8

High-throughput

0.489

High

789661

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

1

High-throughput

0.489

High

789662

DD19B
ATP-dependent RNA helicase DDX19B

1

4

High-throughput

0.489

High

789666

DJC16
DnaJ homolog subfamily C member 16

1

6

High-throughput

0.489

High

789668

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.489

High

130784

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

4

High-throughput

0.437

High

789639

TRM44
Probable tRNA

3

0

High-throughput

0.347

High

789667

LOXL2
Lysyl oxidase homolog 2

3

0

High-throughput

0.347

High

789644

ISOC2
Isochorismatase domain-containing protein 2

2

0

High-throughput

0.318

High

789616

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.282

High

276693

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.279

Low

344794

TIMP1
Metalloproteinase inhibitor 1

1

0

High-throughput

0.279

Low

611991

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.279

Low

621199

KTHY
Thymidylate kinase

1

0

High-throughput

0.279

Low

728894

AHR
Aryl hydrocarbon receptor

1

0

High-throughput

0.279

Low

789612

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.279

Low

789614

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.279

Low

789615

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.279

Low

789627

OZF
Zinc finger protein OZF

1

0

High-throughput

0.279

Low

789632

TATD1
Deoxyribonuclease TATDN1

1

0

High-throughput

0.279

Low

789640

TRM2A
tRNA

1

0

High-throughput

0.279

Low

789650

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.279

Low

789651

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.279

Low

206269

RA51C
DNA repair protein RAD51 homolog 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024