HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: SKI3 (Q6PGP7)
Superkiller complex protein 3 (Ski3) (Tetratricopeptide repeat protein 37) (TPR repeat protein 37) (Tricho-hepatic-enteric syndrome protein) (Thespin)
Gene: SKIC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_1~TPR_16, TPR_1~TPR_8, TPR_16~TPR_6
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 1564
+	Hs
		1053028 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		SKI3_HUMAN (1-1564): 0: 1029: 100.00
+	Hs
		174855 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		OGT1_HUMAN (1-272): 2.04e-16: 87.4: 11.85
+	Hs
		174814 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		OGT1_HUMAN (1-272): 2.04e-16: 87.4: 11.85
+	Hs
		684691 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		STIP1_HUMAN (1-114): 7.91e-10: 65.4: 16.67
+	Hs
		972498 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		IFT88_HUMAN (982-1445): 7.77e-14: 78.9: 10.57
+	Hs
		684646 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		STIP1_HUMAN (1-114): 7.91e-10: 65.4: 16.67
+	Hs
		118697 AIP_HUMAN (144-414): 1.52e-49: 173: 16.72		STIP1_HUMAN (1-114): 7.91e-10: 65.4: 16.67
+	Hs
		684824 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		CTR9_HUMAN (897-1440): 1e-20: 101: 11.01
+	Hs
		174884 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		OGT1_HUMAN (1-272): 2.04e-16: 87.4: 11.85
+	Hs
		174661 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		OGT1_HUMAN (1-272): 2.04e-16: 87.4: 11.85
+	Dm
		817472 FKB12_DROME (153-247): 2.5e-20: 87.6: 26.26		Q9VPN5_DROME (18-425): 1.31e-20: 99.3: 13.26
+	Hs
		684718 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		STIP1_HUMAN (1-114): 7.91e-10: 65.4: 16.67
+	Hs
		684432 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		STIP1_HUMAN (1-114): 7.91e-10: 65.4: 16.67
+	Hs
		645855 FKBP2_HUMAN (153-255): 1.29e-23: 98: 27.52		TTC13_HUMAN (397-689): 7.38e-11: 69.1: 17.22
+	Hs
		175098 FKB10_HUMAN (134-285): 5.25e-13: 72.9: 20.51		OGT1_HUMAN (1-272): 2.04e-16: 87.4: 11.85
+	Hs
		1012412 Q0VDC6_HUMAN (151-247): 5.97e-21: 90.6: 26.73		TMTC1_HUMAN (1-174): 8.71e-10: 65.8: 16.29