HitPredict

Interactor 1: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Interactor 2: SYVC (P26640)
Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS)
Gene: VARS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 441 Hs			1 1264
+	Mm
		1265670 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SYVC_MOUSE (1-1264): 0: 1278: 92.88
+	Hs
		643838 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		SYVC_HUMAN (1-1264): 0: 1282: 100.00
+	Mm
		1207290 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SYIC_MOUSE (292-1206): 0: 805: 19.72
+	Hs
		783084 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SYIC_HUMAN (292-1207): 0: 801: 20.00
+	Mm
		1206904 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SYLC_MOUSE (297-1262): 0: 604: 14.98
+	Hs
		782977 LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69		SYIC_HUMAN (292-1207): 0: 801: 20.00
+	Hs
		783000 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		SYIC_HUMAN (292-1207): 0: 801: 20.00
+	Hs
		1281442 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SYLC_HUMAN (297-1262): 0: 607: 14.73
+	Hs
		1064985 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		SYLM_HUMAN (275-1106): 4.3e-108: 364: 17.30
+	Hs
		267904 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		EF1G_HUMAN (3-275): 6.3e-31: 129: 33.22
+	Mm
		1265532 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		EF1G_MOUSE (3-275): 1.76e-30: 128: 32.88
+	Hs
		644118 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		EF1G_HUMAN (3-275): 6.3e-31: 129: 33.22
+	Hs
		643988 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		EF1G_HUMAN (3-275): 6.3e-31: 129: 33.22