HitPredict

Interactor 1: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Interactor 2: Q9H4D1 (Q9H4D1)
Protein kinase
Gene: dik

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	21931591
Identification Methods	pull down, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 618 Hs			1 784
+	Hs
		883506 BIRC2_HUMAN (1-618): 0: 702: 100.00		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		1206048 MIB1_HUMAN (231-616): 1.49e-51: 193: 15.83		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		1036078 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		201791 BIRC2_HUMAN (1-618): 0: 702: 100.00		RIPK2_HUMAN (31-284): 2.18e-54: 198: 44.36
+	Hs
		883555 MIB1_HUMAN (231-616): 1.49e-51: 193: 15.83		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		883505 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Hs
		1036381 BIRC2_HUMAN (1-618): 0: 702: 100.00		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74
+	Hs
		957782 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		Q9H4D1_HUMAN (1-784): 0: 712: 100.00
+	Hs
		883482 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		RIPK4_HUMAN (1-784): 0: 693: 93.99
+	Mm
		1193396 MIB1_MOUSE (231-616): 1.04e-52: 197: 15.83		DAPK1_MOUSE (464-783): 1.7e-80: 284: 25.39
+	Hs
		862070 MIB1_HUMAN (231-616): 1.49e-51: 193: 15.83		DAPK1_HUMAN (464-783): 4.07e-81: 286: 25.39
+	Hs
		862026 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		DAPK1_HUMAN (464-783): 4.07e-81: 286: 25.39
+	Hs
		201790 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		RIPK2_HUMAN (31-284): 2.18e-54: 198: 44.36
+	Hs
		1036246 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74
+	Hs
		201782 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		RIPK2_HUMAN (31-284): 2.18e-54: 198: 44.36
+	Hs
		257601 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		ANR17_HUMAN (629-784): 6.15e-39: 158: 30.19
+	Hs
		957806 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		RIPK3_HUMAN (21-286): 1.6e-35: 143: 35.74
+	Zm
		36661 C0HHU5_MAIZE (435-618): 5.51e-32: 128: 15.18		A0A1D6M3A7_MAIZE (602-784): 3.9e-25: 114: 20.20
+	Dm
		1097133 DIAP2_DROME (261-462): 3.99e-12: 70.8: 16.99		ANKHM_DROME (363-600): 1.25e-41: 167: 24.59