Protein: TAD2A
Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein)

Gene: TAD2A, TADA2A
Organism: Homo sapiens
Interactions: 205
UniProt ID: O75478

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

283519

KAT2A
Histone acetyltransferase KAT2A

10

20

Small-scale

0.972

High

283520

KAT2B
Histone acetyltransferase KAT2B

6

20

Small-scale

0.940

High

283503

ZZZ3
ZZ-type zinc finger-containing protein 3

4

3

Small-scale

0.867

High

283548

CSR2B
Cysteine-rich protein 2-binding protein

3

3

High-throughput

0.847

High

283474

HDAC1
Histone deacetylase 1

2

13

High-throughput

0.754

High

283527

SGF29
SAGA-associated factor 29

9

4

Small-scale

0.752

High

283404

TADA3
Transcriptional adapter 3

9

7

Small-scale

0.751

High

283455

WDR5
WD repeat-containing protein 5

7

13

Small-scale

0.746

High

283556

MBIP1
MAP3K12-binding inhibitory protein 1

7

3

Small-scale

0.742

High

169352

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

4

3

High-throughput

0.700

High

283461

NC2B
Protein Dr1

4

5

Small-scale

0.686

High

283429

PRS6A
26S proteasome regulatory subunit 6A

3

3

High-throughput

0.667

High

283559

AIRIM
AFG2-interacting ribosome maturation factor

3

0

High-throughput

0.646

High

283569

YETS2
YEATS domain-containing protein 2

3

14

Small-scale

0.640

High

283452

PSME3
Proteasome activator complex subunit 3

3

0

High-throughput

0.638

High

283575

CARD8
Caspase recruitment domain-containing protein 8

3

0

High-throughput

0.638

High

283465

SF3A3
Splicing factor 3A subunit 3

2

1

High-throughput

0.633

High

283517

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

2

High-throughput

0.633

High

283546

IKZF5
Zinc finger protein Pegasus

2

5

High-throughput

0.628

High

283413

MYC
Myc proto-oncogene protein

2

12

Small-scale

0.624

High

283441

HNF4A
Hepatocyte nuclear factor 4-alpha

2

20

Small-scale

0.624

High

246344

KDM1A
Lysine-specific histone demethylase 1A

1

9

High-throughput

0.618

High

283402

TAD2A
Transcriptional adapter 2-alpha

1

15

High-throughput

0.618

High

283475

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.618

High

283500

TAD2B
Transcriptional adapter 2-beta

1

17

High-throughput

0.618

High

283565

RCOR1
REST corepressor 1

1

5

High-throughput

0.618

High

283434

RBTN1
Rhombotin-1

2

10

High-throughput

0.606

High

283469

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

1

High-throughput

0.606

High

283524

MGN2
Protein mago nashi homolog 2

2

1

High-throughput

0.606

High

184666

ATX7
Ataxin-7

2

8

Small-scale

0.584

High

283403

SUPT3
Transcription initiation protein SPT3 homolog

2

4

Small-scale

0.584

High

283445

CDK8
Cyclin-dependent kinase 8

2

4

High-throughput

0.584

High

283451

KLF3
Krueppel-like factor 3

2

16

High-throughput

0.584

High

283483

NF2L2
Nuclear factor erythroid 2-related factor 2

1

10

Small-scale

0.582

High

283494

ZCH12
Zinc finger CCHC domain-containing protein 12

2

0

High-throughput

0.580

High

283511

ZN417
Zinc finger protein 417

2

0

High-throughput

0.580

High

283528

THOC1
THO complex subunit 1

2

0

High-throughput

0.580

High

283541

VPS25
Vacuolar protein-sorting-associated protein 25

2

0

High-throughput

0.580

High

283447

IMA1
Importin subunit alpha-1

1

7

High-throughput

0.573

High

283449

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.573

High

283453

MGN
Protein mago nashi homolog

1

1

High-throughput

0.573

High

283491

ZFY26
Zinc finger FYVE domain-containing protein 26

1

3

High-throughput

0.573

High

283513

CCHCR
Coiled-coil alpha-helical rod protein 1

1

2

High-throughput

0.573

High

283547

CC134
Coiled-coil domain-containing protein 134

1

0

Small-scale

0.561

High

283543

CAD19
Cadherin-19

2

1

High-throughput

0.558

High

283495

PAXI1
PAX-interacting protein 1

1

7

High-throughput

0.552

High

283512

ZN564
Zinc finger protein 564

1

0

High-throughput

0.549

High

283516

TEKT4
Tektin-4

1

0

High-throughput

0.549

High

283530

CDA7L
Cell division cycle-associated 7-like protein

1

0

High-throughput

0.549

High

283537

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

0

High-throughput

0.549

High

283509

MCPH1
Microcephalin

1

2

High-throughput

0.541

High

283551

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

1

10

High-throughput

0.541

High

283425

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

1

High-throughput

0.536

High

283477

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.536

High

283482

MED1
Mediator of RNA polymerase II transcription subunit 1

1

6

High-throughput

0.536

High

283583

KC1G3
Casein kinase I isoform gamma-3

1

4

High-throughput

0.536

High

283458

ACTC
Actin, alpha cardiac muscle 1

2

8

High-throughput

0.533

High

283514

FBF1
Fas-binding factor 1

1

4

High-throughput

0.523

High

283557

KLC4
Kinesin light chain 4

1

2

High-throughput

0.523

High

225505

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

0

High-throughput

0.518

High

283412

F107A
Actin-associated protein FAM107A

1

0

High-throughput

0.518

High

283454

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.513

High

283471

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

283508

HORM2
HORMA domain-containing protein 2

1

0

High-throughput

0.513

High

283555

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.513

High

283561

AATF
Protein AATF

1

1

Small-scale

0.506

High

283415

GCR
Glucocorticoid receptor

1

20

Small-scale

0.501

High

283427

TFE2
Transcription factor E2-alpha

1

4

Small-scale

0.501

High

85931

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

1

High-throughput

0.489

High

185132

FANCG
Fanconi anemia group G protein

1

2

High-throughput

0.481

High

283424

ZN688
Zinc finger protein 688

1

1

High-throughput

0.481

High

283515

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

2

High-throughput

0.481

High

283573

RNF6
E3 ubiquitin-protein ligase RNF6

1

2

High-throughput

0.481

High

65217

HELT
Hairy and enhancer of split-related protein HELT

1

1

High-throughput

0.479

High

141230

DDX3X
ATP-dependent RNA helicase DDX3X

1

3

High-throughput

0.479

High

207381

DHX15
ATP-dependent RNA helicase DHX15

1

3

High-throughput

0.479

High

222403

PLRG1
Pleiotropic regulator 1

1

20

High-throughput

0.479

High

228934

AKAP8
A-kinase anchor protein 8

1

1

High-throughput

0.479

High

238840

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

3

High-throughput

0.479

High

239510

MED14
Mediator of RNA polymerase II transcription subunit 14

1

10

High-throughput

0.479

High

250955

PRP17
Pre-mRNA-processing factor 17

1

20

High-throughput

0.479

High

283405

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

20

High-throughput

0.479

High

283406

MED6
Mediator of RNA polymerase II transcription subunit 6

1

2

High-throughput

0.479

High

283407

ST65G
STAGA complex 65 subunit gamma

1

1

High-throughput

0.479

High

283408

PRP6
Pre-mRNA-processing factor 6

1

3

High-throughput

0.479

High

283409

LC7L3
Luc7-like protein 3

1

1

High-throughput

0.479

High

283411

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.479

High

283416

P53
Cellular tumor antigen p53

1

5

Small-scale

0.479

High

283417

LA
Lupus La protein

1

3

High-throughput

0.479

High

283419

HS90A
Heat shock protein HSP 90-alpha

1

8

High-throughput

0.479

High

283420

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

7

High-throughput

0.479

High

283421

LYN
Tyrosine-protein kinase Lyn

1

5

Small-scale

0.479

High

283422

HS90B
Heat shock protein HSP 90-beta

1

8

High-throughput

0.479

High

283423

SNRPA
U1 small nuclear ribonucleoprotein A

1

2

High-throughput

0.479

High

283426

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

283428

DDX5
Probable ATP-dependent RNA helicase DDX5

1

4

High-throughput

0.479

High

283430

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.479

High

283431

SFPQ
Splicing factor, proline- and glutamine-rich

1

5

High-throughput

0.479

High

283432

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

4

High-throughput

0.479

High

283433

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.479

High

283436

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

High-throughput

0.479

High

283437

ELF1
ETS-related transcription factor Elf-1

1

19

High-throughput

0.479

High

283438

CTNB1
Catenin beta-1

1

8

Small-scale

0.479

High

283439

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

High-throughput

0.479

High

283443

GATA4
Transcription factor GATA-4

1

17

High-throughput

0.479

High

283446

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.479

High

283448

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

1

High-throughput

0.479

High

283456

H4
Histone H4

1

6

High-throughput

0.479

High

283457

TRA2B
Transformer-2 protein homolog beta

1

4

High-throughput

0.479

High

283459

SRSF3
Serine/arginine-rich splicing factor 3

1

3

High-throughput

0.479

High

283460

E2F1
Transcription factor E2F1

1

9

High-throughput

0.479

High

283462

SRSF1
Serine/arginine-rich splicing factor 1

1

3

High-throughput

0.479

High

283463

SRSF4
Serine/arginine-rich splicing factor 4

1

2

High-throughput

0.479

High

283466

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.479

High

283467

ILF3
Interleukin enhancer-binding factor 3

1

5

High-throughput

0.479

High

283468

TAF10
Transcription initiation factor TFIID subunit 10

1

5

High-throughput

0.479

High

283470

SRSF5
Serine/arginine-rich splicing factor 5

1

3

High-throughput

0.479

High

283472

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.479

High

283476

TRA2A
Transformer-2 protein homolog alpha

1

1

High-throughput

0.479

High

283478

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

283479

NONO
Non-POU domain-containing octamer-binding protein

1

5

High-throughput

0.479

High

283480

RNPS1
RNA-binding protein with serine-rich domain 1

1

1

High-throughput

0.479

High

283484

DDB1
DNA damage-binding protein 1

1

5

High-throughput

0.479

High

283485

TAF9
Transcription initiation factor TFIID subunit 9

1

9

High-throughput

0.479

High

283492

MED27
Mediator of RNA polymerase II transcription subunit 27

1

2

High-throughput

0.479

High

283493

EDC4
Enhancer of mRNA-decapping protein 4

1

4

High-throughput

0.479

High

283496

MED25
Mediator of RNA polymerase II transcription subunit 25

1

2

High-throughput

0.479

High

283497

MARK2
Serine/threonine-protein kinase MARK2

1

1

High-throughput

0.479

High

283499

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

7

High-throughput

0.479

High

283502

SRRM1
Serine/arginine repetitive matrix protein 1

1

6

High-throughput

0.479

High

283506

WDTC1
WD and tetratricopeptide repeats protein 1

1

16

High-throughput

0.479

High

283510

SP20H
Transcription factor SPT20 homolog

1

1

High-throughput

0.479

High

283518

PSPC1
Paraspeckle component 1

1

5

High-throughput

0.479

High

283521

DDX17
Probable ATP-dependent RNA helicase DDX17

1

4

High-throughput

0.479

High

283523

MED12
Mediator of RNA polymerase II transcription subunit 12

1

11

High-throughput

0.479

High

283525

PF21A
PHD finger protein 21A

1

13

High-throughput

0.479

High

283526

TADA1
Transcriptional adapter 1

1

2

High-throughput

0.479

High

283529

MED8
Mediator of RNA polymerase II transcription subunit 8

1

2

High-throughput

0.479

High

283532

MED30
Mediator of RNA polymerase II transcription subunit 30

1

1

High-throughput

0.479

High

283534

RBM14
RNA-binding protein 14

1

2

High-throughput

0.479

High

283535

MED15
Mediator of RNA polymerase II transcription subunit 15

1

12

High-throughput

0.479

High

283536

SIN3A
Paired amphipathic helix protein Sin3a

1

7

High-throughput

0.479

High

283538

CDC5L
Cell division cycle 5-like protein

1

14

High-throughput

0.479

High

283539

ELF4
ETS-related transcription factor Elf-4

1

19

High-throughput

0.479

High

283542

MED18
Mediator of RNA polymerase II transcription subunit 18

1

2

High-throughput

0.479

High

283544

MED28
Mediator of RNA polymerase II transcription subunit 28

1

1

High-throughput

0.479

High

283545

RNF41
E3 ubiquitin-protein ligase NRDP1

1

3

High-throughput

0.479

High

283549

MED20
Mediator of RNA polymerase II transcription subunit 20

1

2

High-throughput

0.479

High

283550

TAF9B
Transcription initiation factor TFIID subunit 9B

1

9

High-throughput

0.479

High

283552

SYF1
Pre-mRNA-splicing factor SYF1

1

2

High-throughput

0.479

High

283553

MED4
Mediator of RNA polymerase II transcription subunit 4

1

3

High-throughput

0.479

High

283558

MED17
Mediator of RNA polymerase II transcription subunit 17

1

2

High-throughput

0.479

High

283560

MED29
Mediator of RNA polymerase II transcription subunit 29

1

2

High-throughput

0.479

High

283562

MYEF2
Myelin expression factor 2

1

1

High-throughput

0.479

High

283563

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

High-throughput

0.479

High

283564

PUF60
Poly(U)-binding-splicing factor PUF60

1

1

High-throughput

0.479

High

283566

RALY
RNA-binding protein Raly

1

3

High-throughput

0.479

High

283568

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

High-throughput

0.479

High

283570

PRP19
Pre-mRNA-processing factor 19

1

19

High-throughput

0.479

High

283571

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

6

Small-scale

0.479

High

283572

SRRM2
Serine/arginine repetitive matrix protein 2

1

6

High-throughput

0.479

High

283576

WDR37
WD repeat-containing protein 37

1

19

High-throughput

0.479

High

283577

MED16
Mediator of RNA polymerase II transcription subunit 16

1

2

High-throughput

0.479

High

283578

MED31
Mediator of RNA polymerase II transcription subunit 31

1

4

High-throughput

0.479

High

283579

TRRAP
Transformation/transcription domain-associated protein

1

9

High-throughput

0.479

High

283581

KLF12
Krueppel-like factor 12

1

16

High-throughput

0.479

High

283582

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

5

High-throughput

0.479

High

283418

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

283440

SYUA
Alpha-synuclein

1

0

Small-scale

0.458

High

283464

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.458

High

283481

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.458

High

283522

XPF
DNA repair endonuclease XPF

1

0

High-throughput

0.458

High

283574

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.458

High

3520

A0A0S2Z5X4
Zinc finger protein 688 isoform 4

1

1

High-throughput

0.457

High

283442

MAGAA
Melanoma-associated antigen 10

1

2

High-throughput

0.445

High

187836

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

1

High-throughput

0.437

High

281510

LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4

1

2

High-throughput

0.437

High

283435

MARK3
MAP/microtubule affinity-regulating kinase 3

1

1

High-throughput

0.437

High

283450

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

15

High-throughput

0.437

High

283473

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

12

High-throughput

0.437

High

283488

PRC2B
Protein PRRC2B

1

10

High-throughput

0.437

High

283498

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.437

High

283501

LUZP1
Leucine zipper protein 1

1

6

High-throughput

0.437

High

283540

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.437

High

283554

LUC7L
Putative RNA-binding protein Luc7-like 1

1

1

High-throughput

0.437

High

3239

A0A0S2Z3R2
Fanconi anemia complementation group G

1

2

High-throughput

0.417

High

3265

A0A0S2Z4A7
Fanconi anemia complementation group G isoform 3

1

2

High-throughput

0.417

High

3298

A0A0S2Z4G9
Ring finger protein 6 isoform 2

1

1

High-throughput

0.417

High

283414

IGHG1
Immunoglobulin heavy constant gamma 1

1

1

High-throughput

0.407

High

283533

Q96KY9
CDH19 protein

1

1

High-throughput

0.407

High

283444

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.316

High

283505

CC116
Coiled-coil domain-containing protein 116

2

0

High-throughput

0.316

High

251991

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.299

High

281547

MTX2
Metaxin-2

1

0

High-throughput

0.299

High

283410

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.299

High

283486

RTL8B
Retrotransposon Gag-like protein 8B

1

0

High-throughput

0.299

High

283487

KLH38
Kelch-like protein 38

1

0

High-throughput

0.299

High

283490

TTC23
Tetratricopeptide repeat protein 23

1

0

High-throughput

0.299

High

283507

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.299

High

283580

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.299

High

283504

EXOC8
Exocyst complex component 8

1

0

High-throughput

0.282

High

283567

OGDHL
2-oxoglutarate dehydrogenase-like, mitochondrial

1

0

High-throughput

0.279

Low

283489

YT011
Putative uncharacterized protein MGC163334

1

0

High-throughput

0.268

Low

283531

DOCK6
Dedicator of cytokinesis protein 6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025