HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30581152, 33545068
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 1584
+	Hs
		807713 SQSTM_HUMAN (1-440): 0: 760: 100.00		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Hs
		1036764 SQSTM_HUMAN (1-440): 0: 760: 100.00		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		1037009 SQSTM_HUMAN (1-440): 0: 760: 100.00		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		1036663 SQSTM_HUMAN (1-440): 0: 760: 100.00		NIPBL_HUMAN (588-1406): 4.52e-15: 83.7: 12.73
+	Hs
		319870 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Mm
		1118141 HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50		CE170_MOUSE (1-1584): 0: 592: 88.00
+	Hs
		319840 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03
+	Hs
		1056093 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Mm
		1118155 HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50		ANK2_MOUSE (123-1379): 8.94e-11: 69.4: 13.83
+	Hs
		152570 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		KMT2D_HUMAN (119-1312): 8.58e-09: 62.9: 5.85