HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: WDFY3 (Q8IZQ1)
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Gene: WDFY3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	20971078, 20168092, 24128730, 20417604
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005829 - cytosol GO:0016234 - inclusion body and 2 others more... GO:0016605 - PML body GO:0035973 - aggrephagy
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 3526
+	Hs
		1036634 SQSTM_HUMAN (1-440): 0: 760: 100.00		WDR81_HUMAN (2651-2991): 4.05e-71: 269: 27.73
+	Hs
		1036948 SQSTM_HUMAN (1-440): 0: 760: 100.00		MTMR4_HUMAN (3367-3520): 7.52e-55: 214: 29.07
+	Hs
		319827 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		MTMR3_HUMAN (3275-3521): 1.52e-39: 164: 20.00