Protein: DCD
Dermcidin (EC 3.4.-.-) (Preproteolysin) [Cleaved into: Survival-promoting peptide; DCD-1]

Gene: DCD
Organism: Homo sapiens
Interactions: 222
UniProt ID: P81605

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005216 - monoatomic ion channel activity
GO:0005576 - extracellular region
GO:0006508 - proteolysis
GO:0008233 - peptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

946582

CSN5
COP9 signalosome complex subunit 5

2

1

High-throughput

0.611

High

601210

VDAC1
Voltage-dependent anion-selective channel protein 1

2

0

High-throughput

0.595

High

346502

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.585

High

946598

ZBT18
Zinc finger and BTB domain-containing protein 18

2

1

Small-scale

0.571

High

329635

AGR2
Anterior gradient protein 2 homolog

2

0

Small-scale

0.559

High

946532

LARP7
La-related protein 7

2

0

High-throughput

0.559

High

238549

ANM3
Protein arginine N-methyltransferase 3

1

1

High-throughput

0.536

High

414857

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.536

High

456273

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

1

1

High-throughput

0.536

High

946516

CUL3
Cullin-3

1

2

High-throughput

0.536

High

946517

CUL4B
Cullin-4B

1

2

High-throughput

0.536

High

946568

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.536

High

946626

BAZ2A
Bromodomain adjacent to zinc finger domain protein 2A

1

2

High-throughput

0.536

High

227154

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.533

High

301759

TRI37
E3 ubiquitin-protein ligase TRIM37

2

1

High-throughput

0.533

High

946507

IL24
Interleukin-24

1

0

High-throughput

0.518

High

946632

MRCKB
Serine/threonine-protein kinase MRCK beta

1

1

High-throughput

0.515

High

128534

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.513

High

150097

UTY
Histone demethylase UTY

1

0

High-throughput

0.513

High

363762

ALBU
Albumin

1

0

High-throughput

0.513

High

452735

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

506966

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.513

High

528968

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

725768

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.513

High

946526

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

946546

SMYD5
Histone-lysine N-trimethyltransferase SMYD5

1

0

High-throughput

0.513

High

946553

COX15
Heme A synthase COX15

1

0

High-throughput

0.513

High

946567

PARP8
Protein mono-ADP-ribosyltransferase PARP8

1

0

High-throughput

0.513

High

946595

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

0

High-throughput

0.513

High

946612

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.513

High

946521

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.493

High

946502

RAD51
DNA repair protein RAD51 homolog 1

1

1

High-throughput

0.489

High

946515

CUL2
Cullin-2

1

2

High-throughput

0.489

High

946557

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

1

High-throughput

0.489

High

946565

FANCM
Fanconi anemia group M protein

1

3

High-throughput

0.489

High

946614

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.489

High

946624

WRP73
WD repeat-containing protein WRAP73

1

1

High-throughput

0.489

High

431738

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.480

High

902521

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

946492

DCD
Dermcidin

1

0

Small-scale

0.480

High

946585

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.480

High

130848

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

148673

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

374046

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

377246

GCR
Glucocorticoid receptor

1

1

Small-scale

0.479

High

488677

ARAF
Serine/threonine-protein kinase A-Raf

1

1

High-throughput

0.479

High

708604

MCM5
DNA replication licensing factor MCM5

1

1

High-throughput

0.479

High

832365

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

849995

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

3

High-throughput

0.479

High

867852

HIRA
Protein HIRA

1

2

Small-scale

0.479

High

921523

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.479

High

946506

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

946508

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

Small-scale

0.479

High

946513

IKZF1
DNA-binding protein Ikaros

1

2

High-throughput

0.479

High

946519

DX39B
Spliceosome RNA helicase DDX39B

1

1

High-throughput

0.479

High

946522

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

946529

RBBP7
Histone-binding protein RBBP7

1

2

High-throughput

0.479

High

946533

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

1

High-throughput

0.479

High

946571

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

946590

RNF31
E3 ubiquitin-protein ligase RNF31

1

2

High-throughput

0.479

High

946599

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

946605

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.479

High

946618

DCA13
DDB1- and CUL4-associated factor 13

1

1

High-throughput

0.479

High

946623

MBD5
Methyl-CpG-binding domain protein 5

1

1

High-throughput

0.479

High

946625

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

946627

IKZF3
Zinc finger protein Aiolos

1

2

High-throughput

0.479

High

946629

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

2

Small-scale

0.479

High

946631

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

Small-scale

0.479

High

274728

RA51D
DNA repair protein RAD51 homolog 4

1

1

High-throughput

0.470

High

133976

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.458

High

197276

SERA
D-3-phosphoglycerate dehydrogenase

1

0

Small-scale

0.458

High

298415

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

314303

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.458

High

324340

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

352579

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

361688

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.458

High

396221

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

453280

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

475616

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

503887

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

547535

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

590834

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

650945

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

684629

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

856364

EFNA4
Ephrin-A4

1

0

High-throughput

0.458

High

926919

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

929763

KCNJ2
Inward rectifier potassium channel 2

1

0

Small-scale

0.458

High

946494

VIGLN
Vigilin

1

0

High-throughput

0.458

High

946497

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

946509

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.458

High

946510

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

946511

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

946512

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.458

High

946514

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

946525

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

946539

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.458

High

946541

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

946544

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

946549

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

946558

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

946559

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

946561

GOLI
E3 ubiquitin-protein ligase RNF130

1

0

High-throughput

0.458

High

946563

MILK2
MICAL-like protein 2

1

0

High-throughput

0.458

High

946564

SLX4
Structure-specific endonuclease subunit SLX4

1

0

Small-scale

0.458

High

946570

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

946581

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

946584

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.458

High

946586

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.458

High

946600

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.458

High

946601

INP5K
Inositol polyphosphate 5-phosphatase K

1

0

High-throughput

0.458

High

946602

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

946604

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

946606

PRD14
PR domain zinc finger protein 14

1

0

Small-scale

0.458

High

946607

RNF38
E3 ubiquitin-protein ligase RNF38

1

0

Small-scale

0.458

High

946613

SENP2
Sentrin-specific protease 2

1

0

Small-scale

0.458

High

946615

ISK5
Serine protease inhibitor Kazal-type 5

1

0

Small-scale

0.458

High

946616

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

946597

CK5P2
CDK5 regulatory subunit-associated protein 2

1

2

High-throughput

0.445

High

282620

RNF8
E3 ubiquitin-protein ligase RNF8

1

2

High-throughput

0.437

High

282879

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

1

High-throughput

0.437

High

312569

ARI2
E3 ubiquitin-protein ligase ARIH2

1

2

High-throughput

0.437

High

379274

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

625352

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.437

High

902874

DCAF7
DDB1- and CUL4-associated factor 7

1

3

High-throughput

0.437

High

940777

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

946503

RBBP4
Histone-binding protein RBBP4

1

2

High-throughput

0.437

High

946524

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.437

High

946530

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.437

High

946535

DCA10
DDB1- and CUL4-associated factor 10

1

2

High-throughput

0.437

High

946540

DCAF8
DDB1- and CUL4-associated factor 8

1

2

High-throughput

0.437

High

946550

WDR82
WD repeat-containing protein 82

1

3

High-throughput

0.437

High

946551

LRC31
Leucine-rich repeat-containing protein 31

1

1

High-throughput

0.437

High

946552

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

946577

STAG1
Cohesin subunit SA-1

1

1

High-throughput

0.437

High

946588

MBD6
Methyl-CpG-binding domain protein 6

1

1

High-throughput

0.437

High

946589

SPDLY
Protein Spindly

1

1

High-throughput

0.437

High

946609

TXNIP
Thioredoxin-interacting protein

1

1

Small-scale

0.437

High

946628

FBW1A
F-box/WD repeat-containing protein 1A

1

1

High-throughput

0.437

High

496837

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

563249

ZNF12
Zinc finger protein 12

1

0

High-throughput

0.426

High

853856

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.426

High

887805

CD81
CD81 antigen

1

0

Small-scale

0.426

High

946536

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

946543

RNLS
Renalase

1

0

Small-scale

0.426

High

946566

CNTRB
Centrobin

1

1

High-throughput

0.407

High

946580

ESR2
Estrogen receptor beta

1

1

High-throughput

0.407

High

946592

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.407

High

946505

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.316

High

214215

SPOP
Speckle-type POZ protein

2

0

High-throughput

0.305

High

386513

P53
Cellular tumor antigen p53

2

0

Small-scale

0.305

High

946579

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.299

High

256962

KDM4A
Lysine-specific demethylase 4A

1

0

High-throughput

0.279

Low

327839

CBX7
Chromobox protein homolog 7

1

0

High-throughput

0.279

Low

685903

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.279

Low

946496

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.279

Low

946523

FL2D
Pre-mRNA-splicing regulator WTAP

1

0

High-throughput

0.279

Low

946542

SMBT2
Scm-like with four MBT domains protein 2

1

0

High-throughput

0.279

Low

946555

PIWL4
Piwi-like protein 4

1

0

High-throughput

0.279

Low

946572

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.279

Low

946576

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

High-throughput

0.279

Low

946591

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

946619

ASF1B
Histone chaperone ASF1B

1

0

High-throughput

0.279

Low

946621

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.279

Low

313253

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.269

Low

329152

F107A
Actin-associated protein FAM107A

1

0

High-throughput

0.269

Low

946593

FRMD6
FERM domain-containing protein 6

1

0

High-throughput

0.269

Low

946493

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.253

Low

118550

EYA2
Eyes absent homolog 2

1

0

High-throughput

0.249

Low

224923

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.249

Low

345070

CYTA
Cystatin-A

1

0

High-throughput

0.249

Low

384642

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

456543

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

Small-scale

0.249

Low

552485

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

676734

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

Small-scale

0.249

Low

720223

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

779230

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

795733

MAGA3
Melanoma-associated antigen 3

1

0

Small-scale

0.249

Low

908360

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

933166

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.249

Low

946495

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.249

Low

946498

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.249

Low

946499

DSG1
Desmoglein-1

1

0

High-throughput

0.249

Low

946500

TF65
Transcription factor p65

1

0

Small-scale

0.249

Low

946501

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.249

Low

946504

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.249

Low

946518

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.249

Low

946520

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

946528

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

946531

UVSSA
UV-stimulated scaffold protein A

1

0

Small-scale

0.249

Low

946538

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.249

Low

946547

TET2
Methylcytosine dioxygenase TET2

1

0

Small-scale

0.249

Low

946548

CDC73
Parafibromin

1

0

High-throughput

0.249

Low

946554

DET1
DET1 homolog

1

0

High-throughput

0.249

Low

946556

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.249

Low

946560

WDR5B
WD repeat-containing protein 5B

1

0

High-throughput

0.249

Low

946562

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.249

Low

946573

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.249

Low

946575

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

0

High-throughput

0.249

Low

946578

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.249

Low

946583

TNR14
Tumor necrosis factor receptor superfamily member 14

1

0

High-throughput

0.249

Low

946587

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.249

Low

946594

SPB12
Serpin B12

1

0

High-throughput

0.249

Low

946596

CIC
Protein capicua homolog

1

0

High-throughput

0.249

Low

946603

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.249

Low

946610

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

946611

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

946617

ANLN
Anillin

1

0

High-throughput

0.249

Low

946622

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

0

High-throughput

0.249

Low

946630

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1015

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

200538

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

313416

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.232

Low

946527

T22D1
TSC22 domain family protein 1

1

0

Small-scale

0.232

Low

946534

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.232

Low

946537

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.232

Low

946545

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.232

Low

946569

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low

946574

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.232

Low

946608

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

0

High-throughput

0.232

Low

946620

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.232

Low

831211

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.213

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024