HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: TNPO1 (Q92973)
Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP)
Gene: TNPO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33545068
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 898
+	Hs
		127259 SQSTM_HUMAN (1-440): 0: 760: 100.00		IPO5_HUMAN (21-879): 2.71e-91: 314: 16.85
+	Hs
		1036582 SQSTM_HUMAN (1-440): 0: 760: 100.00		IMB1_HUMAN (21-862): 1.01e-87: 300: 16.15
+	Hs
		312260 SQSTM_HUMAN (1-440): 0: 760: 100.00		IPO7_HUMAN (21-851): 6.08e-77: 273: 14.49
+	Hs
		127267 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		IPO5_HUMAN (21-879): 2.71e-91: 314: 16.85
+	Hs
		1056023 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		IMB1_HUMAN (21-862): 1.01e-87: 300: 16.15
+	Hs
		312269 NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78		IPO7_HUMAN (21-851): 6.08e-77: 273: 14.49