Interactor 1: TRPC3 (Q13507)
Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (TRP-3) (hTrp-3) (hTrp3)
Gene: TRPC3

Interactor 2: ITPR3 (Q14573)
Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)
Gene: ITPR3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.802

The method score is based on:

Property Details
Experiments 11290752, 10611319
Identification Methods pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans
Common GO terms GO:0005886 - plasma membrane
GO:0051592 - response to calcium ion
GO:0070679 - inositol 1,4,5 trisphosphate binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 921
Hs

1 2671
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Last updated: 15 Jul 2024