Protein: GLE1
mRNA export factor GLE1 (hGLE1) (GLE1 RNA export mediator) (GLE1-like protein) (Nucleoporin GLE1)

Gene: GLE1
Organism: Homo sapiens
Interactions: 211
UniProt ID: Q53GS7

Gene Ontology (top 5):
GO:0000822 - inositol hexakisphosphate binding
GO:0005543 - phospholipid binding
GO:0005615 - extracellular space
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1199308

GLE1
mRNA export factor GLE1

1

17

Small-scale

0.752

High

1199391

NXF1
Nuclear RNA export factor 1

4

2

High-throughput

0.691

High

192594

NUP42
Nucleoporin NUP42

4

1

Small-scale

0.687

High

291363

NU155
Nuclear pore complex protein Nup155

4

3

Small-scale

0.685

High

1199336

CARME
Carnosine N-methyltransferase

4

0

High-throughput

0.661

High

1199366

IER2
Immediate early response gene 2 protein

3

0

High-throughput

0.638

High

1037183

H11
Histone H1.1

4

12

High-throughput

0.630

High

1139928

RRS1
Ribosome biogenesis regulatory protein homolog

2

1

High-throughput

0.628

High

1199373

NXF2
Nuclear RNA export factor 2

2

2

High-throughput

0.628

High

1199344

DDX1
ATP-dependent RNA helicase DDX1

1

6

Small-scale

0.618

High

1199402

DD19B
ATP-dependent RNA helicase DDX19B

1

10

High-throughput

0.618

High

809662

RS19
Small ribosomal subunit protein eS19

2

1

High-throughput

0.601

High

1199397

NXT1
NTF2-related export protein 1

2

3

High-throughput

0.601

High

131443

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

4

Small-scale

0.596

High

775552

NU214
Nuclear pore complex protein Nup214

2

14

Small-scale

0.584

High

1007707

RAE1L
mRNA export factor RAE1

2

11

High-throughput

0.584

High

521725

H14
Histone H1.4

2

12

High-throughput

0.574

High

1199338

NUP35
Nucleoporin NUP35

2

0

High-throughput

0.559

High

1199374

MKRN2
E3 ubiquitin-protein ligase makorin-2

2

0

High-throughput

0.559

High

182557

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.536

High

287010

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

12

High-throughput

0.536

High

288665

NPM3
Nucleoplasmin-3

1

2

High-throughput

0.536

High

290586

SURF6
Surfeit locus protein 6

1

2

High-throughput

0.536

High

428797

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

445194

S10A6
Protein S100-A6

1

3

High-throughput

0.536

High

595453

H15
Histone H1.5

1

12

High-throughput

0.536

High

658217

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.536

High

686197

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

788673

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

860775

RS10
Small ribosomal subunit protein eS10

1

6

High-throughput

0.536

High

890334

NU153
Nuclear pore complex protein Nup153

1

15

High-throughput

0.536

High

945242

NU107
Nuclear pore complex protein Nup107

1

2

High-throughput

0.536

High

959813

RS3A
Small ribosomal subunit protein eS1

1

2

High-throughput

0.536

High

975727

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.536

High

978981

RS6
Small ribosomal subunit protein eS6

1

2

High-throughput

0.536

High

981524

RAN
GTP-binding nuclear protein Ran

1

11

High-throughput

0.536

High

985696

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.536

High

1008756

RED1
Double-stranded RNA-specific editase 1

1

10

High-throughput

0.536

High

1016039

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.536

High

1089696

ILF3
Interleukin enhancer-binding factor 3

1

13

High-throughput

0.536

High

1099103

SRSF5
Serine/arginine-rich splicing factor 5

1

14

High-throughput

0.536

High

1134223

IMB1
Importin subunit beta-1

1

7

High-throughput

0.536

High

1178826

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.536

High

1199319

LN28B
Protein lin-28 homolog B

1

3

High-throughput

0.536

High

1199345

FGF13
Fibroblast growth factor 13

1

3

High-throughput

0.536

High

1199349

SEH1
Nucleoporin SEH1

1

11

High-throughput

0.536

High

1199362

MBB1A
Myb-binding protein 1A

1

2

High-throughput

0.536

High

1199369

DUS16
Dual specificity protein phosphatase 16

1

5

High-throughput

0.536

High

1199371

REXO4
RNA exonuclease 4

1

2

High-throughput

0.536

High

1199378

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.536

High

1199381

NXT2
NTF2-related export protein 2

1

3

High-throughput

0.536

High

1199386

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.536

High

1199399

ZN346
Zinc finger protein 346

1

1

High-throughput

0.536

High

1199410

YBOX2
Y-box-binding protein 2

1

3

High-throughput

0.536

High

1199413

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.536

High

1199331

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

7

High-throughput

0.533

High

63298

ODAD3
Outer dynein arm-docking complex subunit 3

1

18

High-throughput

0.515

High

252768

AP180
Clathrin coat assembly protein AP180

1

6

High-throughput

0.515

High

440587

FYN
Tyrosine-protein kinase Fyn

1

3

High-throughput

0.515

High

928469

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.515

High

1028480

BEX3
Protein BEX3

1

1

High-throughput

0.515

High

1157635

BATF
Basic leucine zipper transcriptional factor ATF-like

1

5

High-throughput

0.515

High

1159564

NFE2
Transcription factor NF-E2 45 kDa subunit

1

3

High-throughput

0.515

High

1177565

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

2

High-throughput

0.515

High

1199323

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

1

High-throughput

0.515

High

1199327

Q86V28
AP-1 complex subunit gamma

1

10

High-throughput

0.515

High

1199329

TRI69
E3 ubiquitin-protein ligase TRIM69

1

5

High-throughput

0.515

High

1199332

IFT20
Intraflagellar transport protein 20 homolog

1

1

High-throughput

0.515

High

1199346

RNF34
E3 ubiquitin-protein ligase RNF34

1

1

High-throughput

0.515

High

1199352

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.515

High

1199354

MAGBI
Melanoma-associated antigen B18

1

7

High-throughput

0.515

High

1199372

SKI8
Superkiller complex protein 8

1

16

High-throughput

0.515

High

1199382

RASF1
Ras association domain-containing protein 1

1

4

High-throughput

0.515

High

1199389

MAGC2
Melanoma-associated antigen C2

1

7

High-throughput

0.515

High

1199404

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

High-throughput

0.515

High

1199405

CSN3
COP9 signalosome complex subunit 3

1

2

High-throughput

0.515

High

1199406

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

1

3

High-throughput

0.515

High

1199409

KLH20
Kelch-like protein 20

1

4

High-throughput

0.515

High

1199415

ASB3
Ankyrin repeat and SOCS box protein 3

1

7

High-throughput

0.515

High

1127395

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.513

High

1199334

H18
Histone H1.8

1

0

High-throughput

0.513

High

1199351

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1199364

LLPH
Protein LLP homolog

1

0

High-throughput

0.513

High

1199365

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

1199395

IL17B
Interleukin-17B

1

0

High-throughput

0.513

High

1199401

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

185198

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.493

High

686684

3BHS2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

1

0

High-throughput

0.493

High

907795

CLCN7
H(+)/Cl(-) exchange transporter 7

1

0

High-throughput

0.493

High

946357

FAM3B
Protein FAM3B

1

0

High-throughput

0.493

High

1086607

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.493

High

1199335

FAM9A
Protein FAM9A

1

0

High-throughput

0.493

High

1199339

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.493

High

1199340

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.493

High

1199360

TSNAX
Translin-associated protein X

1

0

High-throughput

0.493

High

1199383

GKN1
Gastrokine-1

1

0

High-throughput

0.493

High

1199392

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.493

High

1199394

RGS17
Regulator of G-protein signaling 17

1

0

High-throughput

0.493

High

1199396

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.493

High

1199414

MTF2
Metal-response element-binding transcription factor 2

1

0

High-throughput

0.493

High

74509

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

10

High-throughput

0.489

High

595794

H13
Histone H1.3

1

12

High-throughput

0.489

High

596137

H12
Histone H1.2

1

12

High-throughput

0.489

High

706145

S10A2
Protein S100-A2

1

3

High-throughput

0.489

High

1062009

SRSF4
Serine/arginine-rich splicing factor 4

1

13

High-throughput

0.489

High

1199328

PNM8A
Paraneoplastic antigen-like protein 8A

1

6

High-throughput

0.489

High

1199355

ZNF48
Zinc finger protein 48

1

2

High-throughput

0.489

High

1199393

ZBT47
Zinc finger and BTB domain-containing protein 47

1

4

High-throughput

0.489

High

566163

K1C10
Keratin, type I cytoskeletal 10

1

14

Small-scale

0.481

High

124790

AIP
AH receptor-interacting protein

1

5

High-throughput

0.479

High

172890

XPO1
Exportin-1

1

6

Small-scale

0.479

High

213464

CTIF
CBP80/20-dependent translation initiation factor

1

4

High-throughput

0.479

High

258914

DNJA2
DnaJ homolog subfamily A member 2

1

3

High-throughput

0.479

High

346641

TTC4
Tetratricopeptide repeat protein 4

1

8

High-throughput

0.479

High

372203

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

460551

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.479

High

542540

TOP2A
DNA topoisomerase 2-alpha

1

2

High-throughput

0.479

High

550314

PABP1
Polyadenylate-binding protein 1

1

7

High-throughput

0.479

High

688254

TTP
mRNA decay activator protein ZFP36

1

2

High-throughput

0.479

High

727832

DNJA1
DnaJ homolog subfamily A member 1

1

3

High-throughput

0.479

High

789127

NUP62
Nuclear pore glycoprotein p62

1

12

High-throughput

0.479

High

810143

RL3
Large ribosomal subunit protein uL3

1

3

High-throughput

0.479

High

828373

PEX19
Peroxisomal biogenesis factor 19

1

1

High-throughput

0.479

High

834464

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

899944

FXR1
RNA-binding protein FXR1

1

8

High-throughput

0.479

High

900357

FXR2
RNA-binding protein FXR2

1

8

High-throughput

0.479

High

901281

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

915971

NUP98
Nuclear pore complex protein Nup98-Nup96

1

11

High-throughput

0.479

High

1004653

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1038633

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

7

High-throughput

0.479

High

1056769

FMR1
Fragile X messenger ribonucleoprotein 1

1

8

High-throughput

0.479

High

1059859

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

5

High-throughput

0.479

High

1101984

PABP4
Polyadenylate-binding protein 4

1

7

High-throughput

0.479

High

1123926

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

6

High-throughput

0.479

High

1129415

PUM1
Pumilio homolog 1

1

1

High-throughput

0.479

High

1161474

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.479

High

1165445

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

7

High-throughput

0.479

High

1199310

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

3

Small-scale

0.479

High

1199314

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

3

High-throughput

0.479

High

1199315

LARP1
La-related protein 1

1

5

High-throughput

0.479

High

1199318

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

1199320

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

3

High-throughput

0.479

High

1199321

NUP54
Nucleoporin p54

1

10

High-throughput

0.479

High

1199324

YTHD3
YTH domain-containing family protein 3

1

8

High-throughput

0.479

High

1199325

PABP2
Polyadenylate-binding protein 2

1

9

High-throughput

0.479

High

1199330

NUDC3
NudC domain-containing protein 3

1

2

High-throughput

0.479

High

1199341

BRX1
Ribosome biogenesis protein BRX1 homolog

1

5

High-throughput

0.479

High

1199342

NU133
Nuclear pore complex protein Nup133

1

2

High-throughput

0.479

High

1199347

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1199353

FUBP3
Far upstream element-binding protein 3

1

11

High-throughput

0.479

High

1199357

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.479

High

1199358

RING2
E3 ubiquitin-protein ligase RING2

1

13

High-throughput

0.479

High

1199359

NUP88
Nuclear pore complex protein Nup88

1

2

High-throughput

0.479

High

1199361

TTC1
Tetratricopeptide repeat protein 1

1

4

High-throughput

0.479

High

1199368

NUP58
Nucleoporin p58/p45

1

5

High-throughput

0.479

High

1199370

UNK
RING finger protein unkempt homolog

1

1

High-throughput

0.479

High

1199375

CCDC8
Coiled-coil domain-containing protein 8

1

6

High-throughput

0.479

High

1199376

ATG5
Autophagy protein 5

1

4

High-throughput

0.479

High

1199377

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.479

High

1199380

MOV10
Helicase MOV-10

1

3

High-throughput

0.479

High

1199385

OCAD1
OCIA domain-containing protein 1

1

2

High-throughput

0.479

High

1199387

BCLF1
Bcl-2-associated transcription factor 1

1

7

High-throughput

0.479

High

1199388

SYLC
Leucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

1199398

AGO2
Protein argonaute-2

1

2

High-throughput

0.479

High

1199403

PRP19
Pre-mRNA-processing factor 19

1

13

High-throughput

0.479

High

1199412

SGT1
Protein SGT1 homolog

1

2

High-throughput

0.479

High

1199416

YTHD2
YTH domain-containing family protein 2

1

10

High-throughput

0.479

High

1199417

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

12

High-throughput

0.479

High

286666

STX11
Syntaxin-11

1

1

High-throughput

0.470

High

297631

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.470

High

302175

NEBL
Nebulette

1

16

High-throughput

0.470

High

666841

CCNC
Cyclin-C

1

2

High-throughput

0.470

High

690707

AOFB
Amine oxidase [flavin-containing] B

1

4

High-throughput

0.470

High

1199311

ZNF57
Zinc finger protein 57

1

1

High-throughput

0.470

High

1199312

LHX8
LIM/homeobox protein Lhx8

1

1

High-throughput

0.470

High

1199337

ZN366
Zinc finger protein 366

1

3

High-throughput

0.470

High

1199343

ING5
Inhibitor of growth protein 5

1

1

High-throughput

0.470

High

1199348

RN183
E3 ubiquitin-protein ligase RNF183

1

1

High-throughput

0.470

High

1199363

Q9BR81
Protocadherin gamma subfamily C, 3

1

1

High-throughput

0.470

High

1199408

ZKSC5
Zinc finger protein with KRAB and SCAN domains 5

1

1

High-throughput

0.470

High

1199390

UXT
Protein UXT

1

0

Small-scale

0.460

High

272947

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.458

High

894791

EMD
Emerin

1

0

High-throughput

0.458

High

951186

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

1032330

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.458

High

1199356

UIF
UAP56-interacting factor

1

0

High-throughput

0.458

High

1199379

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1199326

KTN1
Kinectin

1

17

Small-scale

0.457

High

485184

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

14

High-throughput

0.445

High

601708

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

76121

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

7

High-throughput

0.437

High

283875

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

1

High-throughput

0.437

High

504905

H2AB2
Histone H2A-Bbd type 2/3

1

11

High-throughput

0.437

High

1049160

RON
Macrophage-stimulating protein receptor

1

6

High-throughput

0.437

High

1199384

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.437

High

1199400

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.437

High

1199407

R3HD2
R3H domain-containing protein 2

1

4

High-throughput

0.437

High

1199411

TR150
Thyroid hormone receptor-associated protein 3

1

13

High-throughput

0.437

High

1199313

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

1199367

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

1

6

High-throughput

0.407

High

1199322

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

238714

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

0

High-throughput

0.268

Low

278506

VAMP4
Vesicle-associated membrane protein 4

1

0

High-throughput

0.268

Low

280923

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.268

Low

1199309

TEX35
Testis-expressed protein 35

1

0

High-throughput

0.268

Low

1199333

LAS2
Lung adenoma susceptibility protein 2

1

0

High-throughput

0.268

Low

1199350

REX1B
Required for excision 1-B domain-containing protein

1

0

High-throughput

0.268

Low

1089176

IFRD2
Interferon-related developmental regulator 2

1

0

High-throughput

0.249

Low

1199316

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

0

High-throughput

0.249

Low

1199317

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025