HitPredict

Interactor 1: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25499913, 30166453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 450 Hs			1 1298
+	Hs
		1312801 TBB6_HUMAN (1-446): 0: 700: 92.38		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		903201 TBB3_HUMAN (1-450): 0: 723: 100.00		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		428123 TBB5_HUMAN (1-429): 0: 704: 93.94		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		903115 TBB4B_HUMAN (1-427): 0: 703: 93.91		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		1114123 TBB8_HUMAN (1-427): 0: 705: 87.59		WDR5B_HUMAN (5-294): 1.05e-85: 284: 17.38
+	Hs
		903481 TBB6_HUMAN (1-446): 0: 700: 92.38		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		381159 TBB4A_HUMAN (1-427): 0: 699: 93.21		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		267759 TBB3_HUMAN (1-450): 0: 723: 100.00		TAF5L_HUMAN (57-304): 3.13e-36: 148: 15.14
+	Hs
		267769 TBB8_HUMAN (1-427): 0: 705: 87.59		TAF5L_HUMAN (57-304): 3.13e-36: 148: 15.14
+	Hs
		792969 TBB4B_HUMAN (1-427): 0: 703: 93.91		LIS1_HUMAN (123-346): 3.66e-35: 141: 11.45
+	Hs
		1037374 TBB3_HUMAN (1-450): 0: 723: 100.00		KTNB1_HUMAN (167-610): 7.29e-17: 88: 8.43
+	Hs
		1114214 TBB8_HUMAN (1-427): 0: 705: 87.59		KTNB1_HUMAN (167-610): 7.29e-17: 88: 8.43
+	Hs
		428404 TBB5_HUMAN (1-429): 0: 704: 93.94		KTNB1_HUMAN (167-610): 7.29e-17: 88: 8.43
+	Hs
		1046536 TBB2A_HUMAN (1-430): 0: 700: 93.49		FBXW7_HUMAN (164-329): 5.74e-18: 91.8: 9.58
+	Hs
		1281356 TBB6_HUMAN (1-446): 0: 700: 92.38		FBXW7_HUMAN (164-329): 5.74e-18: 91.8: 9.58
+	Hs
		933952 TBB4B_HUMAN (1-427): 0: 703: 93.91		KTNB1_HUMAN (167-610): 7.29e-17: 88: 8.43
+	Hs
		381262 TBB4A_HUMAN (1-427): 0: 699: 93.21		FBXW7_HUMAN (164-329): 5.74e-18: 91.8: 9.58
+	Hs
		1046564 TBB2A_HUMAN (1-430): 0: 700: 93.49		KTNB1_HUMAN (167-610): 7.29e-17: 88: 8.43
+	Hs
		1312794 TBB6_HUMAN (1-446): 0: 700: 92.38		KTNB1_HUMAN (167-610): 7.29e-17: 88: 8.43
+	Hs
		1114207 TBB8_HUMAN (1-427): 0: 705: 87.59		TBL1Y_HUMAN (5-169): 1.78e-13: 76.7: 21.67