Interactor 1: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1
Interactor 2: TRADD (Q15628)
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain)
Gene: TRADD
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.965 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27768232, 8612133, 30561431, 23429285, 16603398, 21724995, 24735611 |
| Identification Methods | affinity chromatography technology, two hybrid, experimental interaction detection, anti tag coimmunoprecipitation, virotrap, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Death~Death |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006915 - apoptotic process GO:0031264 - death-inducing signaling complex GO:0033209 - tumor necrosis factor-mediated signaling pathway and 9 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
