HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1128
+	Hs
		910195 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		927696 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		684376 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ZO2_HUMAN (33-1124): 2.95e-51: 199: 12.79
+	Hs
		910124 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ZO2_HUMAN (33-1124): 2.95e-51: 199: 12.79
+	Hs
		684280 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MAGI1_HUMAN (216-1126): 8.38e-41: 166: 12.95
+	Hs
		927623 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ZO2_HUMAN (33-1124): 2.95e-51: 199: 12.79
+	Hs
		684030 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SCRIB_HUMAN (673-1100): 2.61e-27: 122: 17.81
+	Hs
		684003 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PTN13_HUMAN (18-280): 1.38e-22: 107: 18.56
+	Hs
		684204 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		LNX2_HUMAN (5-132): 1.05e-13: 77.8: 19.85
+	Hs
		909498 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PTN13_HUMAN (18-280): 1.38e-22: 107: 18.56
+	Mm
		250606 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		LNX1_MOUSE (13-235): 2.92e-29: 127: 23.92
+	Hs
		927034 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SCRIB_HUMAN (673-1100): 2.61e-27: 122: 17.81
+	Mm
		910260 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		926984 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PTN13_HUMAN (18-280): 1.38e-22: 107: 18.56
+	Dm
		677686 1433E_DROME (2-247): 2.8e-144: 405: 58.07		DLG1_DROME (656-790): 7.8e-11: 68.8: 24.11
+	Mm
		926805 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		927328 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		LNX1_HUMAN (777-1113): 2.02e-11: 70.4: 14.08
+	Mm
		926859 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		LNX2_MOUSE (916-1116): 1.03e-10: 67.8: 13.59
+	Hs
		646881 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		SCRIB_HUMAN (673-1100): 2.61e-27: 122: 17.81
+	Hs
		646848 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		PTN13_HUMAN (18-280): 1.38e-22: 107: 18.56