HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 661
+	Hs
		245600 HDAC1_HUMAN (1-482): 0: 668: 100.00		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		245623 HDAC2_HUMAN (1-478): 0: 666: 85.92		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		1270358 HDAC2_HUMAN (1-478): 0: 666: 85.92		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		903202 HDAC1_HUMAN (1-482): 0: 668: 100.00		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		903404 HDAC2_HUMAN (1-478): 0: 666: 85.92		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		177148 HDAC3_HUMAN (9-434): 0: 574: 57.94		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Dm
		1182201 Q7KTS4_DROME (7-435): 0: 564: 56.52		EBI_DROME (383-661): 4.41e-63: 223: 18.27
+	Hs
		177369 HDAC3_HUMAN (9-434): 0: 574: 57.94		TBL1Y_HUMAN (396-661): 1.24e-60: 213: 19.72
+	Dm
		1279322 Q9VNC2_DROME (7-435): 0: 560: 56.29		EBI_DROME (383-661): 4.41e-63: 223: 18.27
+	Hs
		1038460 HDAC1_HUMAN (1-482): 0: 668: 100.00		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Hs
		1146689 HDAC2_HUMAN (1-478): 0: 666: 85.92		A16L1_HUMAN (522-652): 1.81e-24: 110: 18.94
+	Mm
		140299 HDAC1_MOUSE (1-482): 0: 672: 99.38		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Hs
		282986 HDAC2_HUMAN (1-478): 0: 666: 85.92		CIAO1_HUMAN (359-641): 1.55e-15: 80.5: 26.18
+	Mm
		936414 HDAC2_MOUSE (1-478): 0: 664: 85.71		A16L1_MOUSE (356-473): 6.39e-15: 80.1: 19.67
+	Hs
		1270370 HDAC2_HUMAN (1-478): 0: 666: 85.92		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Hs
		177249 HDAC3_HUMAN (9-434): 0: 574: 57.94		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Sc
		561855 RPD3_YEAST (8-421): 0: 580: 61.48		TUP1_YEAST (363-641): 1.07e-12: 73.2: 26.26
+	Hs
		245622 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		1260173 HDAC7_HUMAN (10-410): 1.09e-137: 421: 21.56		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Sc
		561895 HDA1_YEAST (10-329): 4.19e-119: 366: 26.74		TUP1_YEAST (363-641): 1.07e-12: 73.2: 26.26