HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: SP30L (Q9HAJ7)
Histone deacetylase complex subunit SAP30L (HCV non-structural protein 4A-transactivated protein 2) (Sin3 corepressor complex subunit SAP30L) (Sin3-associated protein p30-like)
Gene: SAP30L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 16820529, 28514442, 33961781, 35271311, 23752268
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030336 - negative regulation of cell migration
and 3 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 482
Hs

1 183
+ Hs
+ Hs
+ Mm
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+ Mm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024