HitPredict

Interactor 1: KCC2B (Q13554)
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)
Gene: CAMK2B

Interactor 2: KCC2B (Q13554)
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)
Gene: CAMK2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.889

The method score is based on:

Property Details
Experiments 25416956, 36949045, 15604093, 20668654
Identification Methods two hybrid, two hybrid array, cosedimentation in solution
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CaMKII_AD~CaMKII_AD, CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0003779 - actin binding
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
and 26 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 666
Hs

1 666
+ Ce
+ Hs
+ Hs
+ Hs
+ At
+ Rn
+ Gm
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024