HitPredict

Interactor 1: KCC2D (Q13557)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: CAMK2D

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	35563538, 37207277
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 768
+	Hs
		1038958 KCC2G_HUMAN (1-478): 0: 646: 75.45		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1038959 KCC2G_HUMAN (1-478): 0: 646: 75.45		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1039056 KCC2D_HUMAN (1-499): 0: 606: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043312 KCC2A_HUMAN (1-474): 0: 541: 87.37		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1041970 KCC1D_HUMAN (14-307): 3.56e-73: 238: 42.18		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041539 KCC1A_HUMAN (12-307): 1.69e-70: 230: 43.10		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1038865 KCC2B_HUMAN (228-478): 1.5e-64: 223: 50.20		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1038866 KCC2B_HUMAN (228-478): 1.5e-64: 223: 50.20		CUL4A_HUMAN (10-768): 0: 791: 38.32