HitPredict

Interactor 1: LAPM5 (Q13571)
Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein)
Gene: LAPTM5

Interactor 2: WWP1 (Q9H0M0)
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
Gene: WWP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15231748
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 922
+	Hs
		1039511 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		125438 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		1039512 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		NED4L_HUMAN (1-919): 0: 822: 33.16
+	Hs
		808116 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		808158 Q5TBB8_HUMAN (1-262): 2.03e-151: 424: 100.00		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Mm
		808355 LAPM5_MOUSE (1-262): 4.27e-144: 405: 79.01		NEDD4_MOUSE (3-446): 4.73e-51: 195: 18.83
+	Hs
		1039518 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		SMUF2_HUMAN (7-381): 2.95e-31: 133: 16.24