Protein: E9PAV9
G patch domain-containing protein 4

Gene: E9PAV9, GPATCH4
Organism: Homo sapiens
Interactions: 230
UniProt ID: E9PAV9

Gene Ontology (top 5):
GO:0003676 - nucleic acid binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

96739

DDX27
Probable ATP-dependent RNA helicase DDX27

2

2

High-throughput

0.754

High

96761

DDX24
ATP-dependent RNA helicase DDX24

2

2

High-throughput

0.754

High

96766

DDX31
ATP-dependent DNA helicase DDX31

2

2

High-throughput

0.754

High

96772

DDX21
Nucleolar RNA helicase 2

2

2

High-throughput

0.754

High

96781

DDX56
Probable ATP-dependent RNA helicase DDX56

2

5

High-throughput

0.754

High

96594

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

5

8

High-throughput

0.641

High

96605

NPM
Nucleophosmin

3

1

High-throughput

0.640

High

96648

RS6
Small ribosomal subunit protein eS6

3

1

High-throughput

0.640

High

96776

NLE1
Notchless protein homolog 1

3

3

High-throughput

0.640

High

96680

DHX8
ATP-dependent RNA helicase DHX8

1

1

High-throughput

0.618

High

96796

DDX52
Probable ATP-dependent RNA helicase DDX52

1

1

High-throughput

0.618

High

96612

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

0

High-throughput

0.613

High

96629

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.586

High

96672

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.586

High

96755

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.586

High

96576

NOP56
Nucleolar protein 56

2

1

High-throughput

0.584

High

96579

NVL
Nuclear valosin-containing protein-like

2

2

High-throughput

0.584

High

96583

RRP8
Ribosomal RNA-processing protein 8

2

2

High-throughput

0.584

High

96586

Z354A
Zinc finger protein 354A

2

8

High-throughput

0.584

High

96589

SURF6
Surfeit locus protein 6

2

2

High-throughput

0.584

High

96598

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

96622

RL4
Large ribosomal subunit protein uL4

2

2

High-throughput

0.584

High

96645

RS8
Small ribosomal subunit protein eS8

2

2

High-throughput

0.584

High

96647

RL7A
Large ribosomal subunit protein eL8

2

2

High-throughput

0.584

High

96653

RL31
Large ribosomal subunit protein eL31

2

1

High-throughput

0.584

High

96657

H31
Histone H3.1

2

2

High-throughput

0.584

High

96658

NOP14
Nucleolar protein 14

2

2

High-throughput

0.584

High

96666

CEBPZ
CCAAT/enhancer-binding protein zeta

2

2

High-throughput

0.584

High

96677

NOG2
Nucleolar GTP-binding protein 2

2

2

High-throughput

0.584

High

96683

RRS1
Ribosome biogenesis regulatory protein homolog

2

2

High-throughput

0.584

High

96685

PWP2
Periodic tryptophan protein 2 homolog

2

5

High-throughput

0.584

High

96686

TTF1
Transcription termination factor 1

2

3

High-throughput

0.584

High

96687

PUM3
Pumilio homolog 3

2

2

High-throughput

0.584

High

96694

RRP12
RRP12-like protein

2

2

High-throughput

0.584

High

96697

SPT2
Protein SPT2 homolog

2

2

High-throughput

0.584

High

96699

NEPRO
Nucleolus and neural progenitor protein

2

2

High-throughput

0.584

High

96700

CC137
Coiled-coil domain-containing protein 137

2

2

High-throughput

0.584

High

96716

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

2

2

High-throughput

0.584

High

96725

NGDN
Neuroguidin

2

2

High-throughput

0.584

High

96729

BRX1
Ribosome biogenesis protein BRX1 homolog

2

7

High-throughput

0.584

High

96731

NOC3L
Nucleolar complex protein 3 homolog

2

8

High-throughput

0.584

High

96750

EBP2
Probable rRNA-processing protein EBP2

2

2

High-throughput

0.584

High

96752

MBB1A
Myb-binding protein 1A

2

2

High-throughput

0.584

High

96756

NOC4L
Nucleolar complex protein 4 homolog

2

8

High-throughput

0.584

High

96758

MAK16
Protein MAK16 homolog

2

2

High-throughput

0.584

High

96759

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

2

4

High-throughput

0.584

High

96760

GTPB4
GTP-binding protein 4

2

2

High-throughput

0.584

High

96764

GZF1
GDNF-inducible zinc finger protein 1

2

11

High-throughput

0.584

High

96765

RPF2
Ribosome production factor 2 homolog

2

2

High-throughput

0.584

High

96768

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

2

2

High-throughput

0.584

High

96777

RBM28
RNA-binding protein 28

2

5

High-throughput

0.584

High

96788

NOL12
Nucleolar protein 12

2

2

High-throughput

0.584

High

96789

NUFP1
FMR1-interacting protein NUFIP1

2

2

High-throughput

0.584

High

96798

RBMX2
RNA-binding motif protein, X-linked 2

2

2

High-throughput

0.584

High

96802

RBM19
Probable RNA-binding protein 19

2

2

High-throughput

0.584

High

96706

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.553

High

96714

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.553

High

96643

RL15
Large ribosomal subunit protein eL15

2

2

High-throughput

0.533

High

96667

ZNF92
Zinc finger protein 92

2

5

High-throughput

0.533

High

96708

ZCCHV
Zinc finger CCCH-type antiviral protein 1

2

4

High-throughput

0.533

High

96723

ZFP62
Zinc finger protein 62 homolog

2

8

High-throughput

0.533

High

96732

BBX
HMG box transcription factor BBX

2

2

High-throughput

0.533

High

96742

ZN845
Zinc finger protein 845

2

11

High-throughput

0.533

High

96743

ZN668
Zinc finger protein 668

2

11

High-throughput

0.533

High

96745

ZN512
Zinc finger protein 512

2

11

High-throughput

0.533

High

96775

ZN701
Zinc finger protein 701

2

14

High-throughput

0.533

High

96784

ZN624
Zinc finger protein 624

2

8

High-throughput

0.533

High

96791

HERC5
E3 ISG15--protein ligase HERC5

2

3

High-throughput

0.533

High

96795

RL26L
Ribosomal protein uL24-like

2

1

High-throughput

0.533

High

96721

KASH5
Protein KASH5

2

1

High-throughput

0.533

High

96727

CEP70
Centrosomal protein of 70 kDa

2

2

High-throughput

0.533

High

96578

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

96584

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

6

High-throughput

0.479

High

96587

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.479

High

96588

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

96590

RL1D1
Ribosomal L1 domain-containing protein 1

1

3

High-throughput

0.479

High

96592

NSA2
Ribosome biogenesis protein NSA2 homolog

1

1

High-throughput

0.479

High

96593

KLF8
Krueppel-like factor 8

1

7

High-throughput

0.479

High

96596

CHK2
Serine/threonine-protein kinase Chk2

1

1

High-throughput

0.479

High

96597

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

High-throughput

0.479

High

96600

ESR1
Estrogen receptor

1

2

High-throughput

0.479

High

96602

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

96607

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

96610

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

96613

SP100
Nuclear autoantigen Sp-100

1

1

High-throughput

0.479

High

96614

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

96615

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

96625

MNDA
Myeloid cell nuclear differentiation antigen

1

2

High-throughput

0.479

High

96626

RBM34
RNA-binding protein 34

1

1

High-throughput

0.479

High

96627

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.479

High

96628

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.479

High

96630

NOP2
28S rRNA

1

1

High-throughput

0.479

High

96634

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

96641

PRD15
PR domain zinc finger protein 15

1

10

High-throughput

0.479

High

96642

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

96656

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.479

High

96659

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.479

High

96660

H33
Histone H3.3

1

2

High-throughput

0.479

High

96662

H11
Histone H1.1

1

1

High-throughput

0.479

High

96665

TOP2B
DNA topoisomerase 2-beta

1

1

High-throughput

0.479

High

96669

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.479

High

96671

GRSF1
G-rich sequence factor 1

1

3

High-throughput

0.479

High

96673

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

96675

CUL1
Cullin-1

1

3

High-throughput

0.479

High

96676

CUL3
Cullin-3

1

3

High-throughput

0.479

High

96678

KLF9
Krueppel-like factor 9

1

7

High-throughput

0.479

High

96681

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

96688

TRBP2
RISC-loading complex subunit TARBP2

1

8

High-throughput

0.479

High

96690

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.479

High

96692

GLYR1
Cytokine-like nuclear factor N-PAC

1

1

High-throughput

0.479

High

96698

RL7L
Ribosomal protein uL30-like

1

1

High-throughput

0.479

High

96701

BCOR
BCL-6 corepressor

1

1

Small-scale

0.479

High

96703

PAXI1
PAX-interacting protein 1

1

2

High-throughput

0.479

High

96707

ZN771
Zinc finger protein 771

1

4

High-throughput

0.479

High

96717

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

96719

ZCHC9
Zinc finger CCHC domain-containing protein 9

1

1

High-throughput

0.479

High

96720

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

9

High-throughput

0.479

High

96724

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.479

High

96726

NUP43
Nucleoporin Nup43

1

5

High-throughput

0.479

High

96728

NEIL3
Endonuclease 8-like 3

1

1

High-throughput

0.479

High

96733

DGCR8
Microprocessor complex subunit DGCR8

1

1

High-throughput

0.479

High

96734

TOPB1
DNA topoisomerase 2-binding protein 1

1

2

High-throughput

0.479

High

96735

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

96736

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.479

High

96737

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

4

High-throughput

0.479

High

96738

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.479

High

96747

UIF
UAP56-interacting factor

1

1

High-throughput

0.479

High

96749

POP1
Ribonucleases P/MRP protein subunit POP1

1

1

High-throughput

0.479

High

96751

RBM4B
RNA-binding protein 4B

1

1

High-throughput

0.479

High

96753

BUD13
BUD13 homolog

1

1

High-throughput

0.479

High

96754

UTP23
rRNA-processing protein UTP23 homolog

1

3

High-throughput

0.479

High

96763

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.479

High

96767

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

96771

SSF1
Suppressor of SWI4 1 homolog

1

1

High-throughput

0.479

High

96773

RED2
Double-stranded RNA-specific editase B2

1

6

High-throughput

0.479

High

96774

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

8

High-throughput

0.479

High

96779

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.479

High

96780

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.479

High

96786

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.479

High

96794

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.479

High

96797

FCF1
rRNA-processing protein FCF1 homolog

1

3

High-throughput

0.479

High

96800

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.479

High

96801

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

High-throughput

0.479

High

96757

KLF16
Krueppel-like factor 16

1

7

High-throughput

0.470

High

96574

MEN1
Menin

1

0

High-throughput

0.458

High

96580

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

96582

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

96591

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

Small-scale

0.458

High

96599

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

96606

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

96609

MYB
Transcriptional activator Myb

1

0

High-throughput

0.458

High

96617

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

96618

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

96620

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

96621

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

96623

COIL
Coilin

1

0

High-throughput

0.458

High

96624

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

96631

CRKL
Crk-like protein

1

0

High-throughput

0.458

High

96633

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

96635

ARL4D
ADP-ribosylation factor-like protein 4D

1

0

High-throughput

0.458

High

96638

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

96639

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

96640

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

96649

H4
Histone H4

1

0

High-throughput

0.458

High

96650

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

96651

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

96668

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

96674

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

96682

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

96689

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

96693

MIDN
Midnolin

1

0

High-throughput

0.458

High

96710

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

96715

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

96722

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

96730

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

96741

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

96748

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

96762

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

96770

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.458

High

96778

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

96782

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

96783

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

96787

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

96792

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

96799

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

96581

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.437

High

96595

DDAH2
Putative hydrolase DDAH2

1

1

High-throughput

0.437

High

96604

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.437

High

96608

H2A1
Histone H2A type 1

1

3

High-throughput

0.437

High

96636

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.437

High

96637

OAZ1
Ornithine decarboxylase antizyme 1

1

1

High-throughput

0.437

High

96644

RL37A
Large ribosomal subunit protein eL43

1

1

High-throughput

0.437

High

96652

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.437

High

96654

RL10A
Large ribosomal subunit protein uL1

1

3

High-throughput

0.437

High

96655

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.437

High

96663

RL18A
Large ribosomal subunit protein eL20

1

1

High-throughput

0.437

High

96679

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.437

High

96691

RN151
RING finger protein 151

1

1

High-throughput

0.437

High

96695

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

High-throughput

0.437

High

96696

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

96705

H1FNT
Testis-specific H1 histone

1

1

High-throughput

0.437

High

96709

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

96712

TAXB1
Tax1-binding protein 1

1

1

High-throughput

0.437

High

96713

H2A2B
Histone H2A type 2-B

1

3

High-throughput

0.437

High

96744

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

1

High-throughput

0.437

High

96746

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

1

High-throughput

0.437

High

96769

RC3H2
Roquin-2

1

1

High-throughput

0.437

High

96785

MYEF2
Myelin expression factor 2

1

1

High-throughput

0.437

High

96793

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

96803

PCDBF
Protocadherin beta-15

1

1

High-throughput

0.437

High

96632

NEST
Nestin

1

0

High-throughput

0.279

Low

96718

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.269

Low

96575

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.249

Low

96577

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

96585

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

96601

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

96603

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

96611

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.249

Low

96616

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

96619

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

96646

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

96661

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

96664

HEN1
Helix-loop-helix protein 1

1

0

High-throughput

0.249

Low

96670

ARL16
ADP-ribosylation factor-like protein 16

1

0

High-throughput

0.249

Low

96684

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

96702

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

96704

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

96711

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

96740

PRR11
Proline-rich protein 11

1

0

High-throughput

0.249

Low

96790

XPO7
Exportin-7

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025