HitPredict

Interactor 1: PWP1 (Q13610)
Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502)
Gene: PWP1

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	31973889, 33355139, 17079684, 21145461, 19295130
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 Hs			1 759
+	Hs
		792982 LIS1_HUMAN (25-461): 1.23e-81: 261: 12.94		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043085 WDR5B_HUMAN (28-370): 4.44e-55: 189: 12.68		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043499 FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043157 SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043441 WDR5B_HUMAN (28-370): 4.44e-55: 189: 12.68		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		245601 TBL1X_HUMAN (26-374): 1.02e-50: 183: 15.10		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		920959 GBB1_HUMAN (247-492): 2.59e-37: 141: 15.75		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043234 GBB4_HUMAN (247-492): 1.14e-36: 140: 16.10		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		921556 GBB2_HUMAN (247-492): 1.81e-36: 139: 15.75		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043509 SNR40_HUMAN (16-369): 1.71e-44: 162: 14.88		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043562 TBL1R_HUMAN (7-331): 4.59e-39: 150: 14.89		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1040789 PWP1_HUMAN (299-500): 6.9e-30: 124: 13.91		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1041647 TAF5_HUMAN (66-363): 3.47e-40: 156: 15.95		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1041133 FBXW7_HUMAN (76-454): 3.52e-64: 222: 16.09		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		920958 GBB1_HUMAN (247-492): 2.59e-37: 141: 15.75		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		921555 GBB2_HUMAN (247-492): 1.81e-36: 139: 15.75		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Mm
		1257398 FBXW7_MOUSE (13-409): 2.33e-57: 204: 12.10		CUL1_MOUSE (59-759): 0: 745: 30.55
+	Hs
		1040787 PWP1_HUMAN (299-500): 6.9e-30: 124: 13.91		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1042101 POC1B_HUMAN (7-267): 3.42e-21: 98.1: 10.57		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1040786 PWP1_HUMAN (299-500): 6.9e-30: 124: 13.91		CUL1_HUMAN (59-759): 0: 745: 30.55