HitPredict

Interactor 1: MTMR2 (Q13614)
Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)
Gene: MTMR2

Interactor 2: MTMR2 (Q13614)
Myotubularin-related protein 2 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)
Gene: MTMR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 27432908, 12668758
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GRAM~Myotub-related, Myotub-related~Myotub-related
Common GO terms GO:0002091 - negative regulation of receptor internalization
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005774 - vacuolar membrane
and 26 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 643
Hs

1 643
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024