Protein: ELK3
ETS domain-containing protein Elk-3 (ETS-related protein ERP) (ETS-related protein NET) (Serum response factor accessory protein 2) (SAP-2) (SRF accessory protein 2)

Gene: ELK3
Organism: Homo sapiens
Interactions: 117
UniProt ID: P41970

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

837034

FOXK1
Forkhead box protein K1

1

16

High-throughput

0.618

High

837040

GABPA
GA-binding protein alpha chain

1

17

High-throughput

0.618

High

837051

BCORL
BCL-6 corepressor-like protein 1

1

9

High-throughput

0.618

High

837057

BCOR
BCL-6 corepressor

1

15

High-throughput

0.618

High

837065

FOXP4
Forkhead box protein P4

1

20

High-throughput

0.618

High

837078

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

11

High-throughput

0.618

High

837089

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.618

High

837091

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

11

High-throughput

0.618

High

837037

SP4
Transcription factor Sp4

2

20

High-throughput

0.606

High

837082

PFD5
Prefoldin subunit 5

2

1

High-throughput

0.606

High

837112

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

2

7

Small-scale

0.584

High

142882

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.578

High

837041

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.578

High

699626

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

1

High-throughput

0.576

High

837024

CRK
Adapter molecule crk

1

7

High-throughput

0.568

High

473841

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.561

High

837067

ASXL1
Polycomb group protein ASXL1

1

7

High-throughput

0.552

High

421655

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

65711

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

3

High-throughput

0.479

High

130711

TAF4
Transcription initiation factor TFIID subunit 4

1

15

High-throughput

0.479

High

175855

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

High-throughput

0.479

High

194520

KDM6A
Lysine-specific demethylase 6A

1

8

High-throughput

0.479

High

229310

ZBT14
Zinc finger and BTB domain-containing protein 14

1

1

High-throughput

0.479

High

245597

ZEB2
Zinc finger E-box-binding homeobox 2

1

5

High-throughput

0.479

High

277156

ZN217
Zinc finger protein 217

1

1

High-throughput

0.479

High

282683

E2F6
Transcription factor E2F6

1

6

High-throughput

0.479

High

297497

PIAS1
E3 SUMO-protein ligase PIAS1

1

14

High-throughput

0.479

High

297770

PIAS2
E3 SUMO-protein ligase PIAS2

1

14

High-throughput

0.479

High

344882

WIZ
Protein Wiz

1

10

High-throughput

0.479

High

505531

ATX1L
Ataxin-1-like

1

10

High-throughput

0.479

High

559736

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

13

High-throughput

0.479

High

576184

PO2F1
POU domain, class 2, transcription factor 1

1

14

High-throughput

0.479

High

586244

ZEP1
Zinc finger protein 40

1

7

High-throughput

0.479

High

587425

TFE2
Transcription factor E2-alpha

1

2

Small-scale

0.479

High

593932

NCK1
SH2/SH3 adapter protein NCK1

1

4

High-throughput

0.479

High

639678

TAF1
Transcription initiation factor TFIID subunit 1

1

20

High-throughput

0.479

High

674103

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

675396

TYY1
Transcriptional repressor protein YY1

1

10

High-throughput

0.479

High

837025

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

13

High-throughput

0.479

High

837026

TAF6
Transcription initiation factor TFIID subunit 6

1

5

High-throughput

0.479

High

837027

MNX1
Motor neuron and pancreas homeobox protein 1

1

20

High-throughput

0.479

High

837028

ZN131
Zinc finger protein 131

1

7

High-throughput

0.479

High

837029

HIRA
Protein HIRA

1

14

High-throughput

0.479

High

837030

ATX1
Ataxin-1

1

10

High-throughput

0.479

High

837031

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.479

High

837032

GRB2
Growth factor receptor-bound protein 2

1

8

High-throughput

0.479

High

837035

TFAM
Transcription factor A, mitochondrial

1

16

High-throughput

0.479

High

837036

SP2
Transcription factor Sp2

1

20

High-throughput

0.479

High

837038

MECOM
Histone-lysine N-methyltransferase MECOM

1

2

High-throughput

0.479

High

837039

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

837042

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.479

High

837044

PWP1
Periodic tryptophan protein 1 homolog

1

20

High-throughput

0.479

High

837045

VEZF1
Vascular endothelial zinc finger 1

1

1

High-throughput

0.479

High

837046

RBBP5
Retinoblastoma-binding protein 5

1

11

High-throughput

0.479

High

837047

TAF5
Transcription initiation factor TFIID subunit 5

1

15

High-throughput

0.479

High

837048

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

6

High-throughput

0.479

High

837050

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

837052

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

7

High-throughput

0.479

High

837053

TAF3
Transcription initiation factor TFIID subunit 3

1

20

High-throughput

0.479

High

837054

LIN54
Protein lin-54 homolog

1

4

High-throughput

0.479

High

837055

ZN746
Zinc finger protein 746

1

3

High-throughput

0.479

High

837056

TAF2
Transcription initiation factor TFIID subunit 2

1

4

High-throughput

0.479

High

837058

POGZ
Pogo transposable element with ZNF domain

1

4

High-throughput

0.479

High

837060

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

837061

I2BP2
Interferon regulatory factor 2-binding protein 2

1

5

High-throughput

0.479

High

837062

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

837063

ZFHX4
Zinc finger homeobox protein 4

1

5

High-throughput

0.479

High

837064

I2BP1
Interferon regulatory factor 2-binding protein 1

1

1

High-throughput

0.479

High

837066

MGAP
MAX gene-associated protein

1

8

High-throughput

0.479

High

837068

SP20H
Transcription factor SPT20 homolog

1

2

High-throughput

0.479

High

837069

KDM2B
Lysine-specific demethylase 2B

1

16

High-throughput

0.479

High

837070

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

10

High-throughput

0.479

High

837071

MORC4
MORC family CW-type zinc finger protein 4

1

3

High-throughput

0.479

High

837072

GATD1
GATA zinc finger domain-containing protein 1

1

4

High-throughput

0.479

High

837073

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

837074

RREB1
Ras-responsive element-binding protein 1

1

3

High-throughput

0.479

High

837075

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

12

High-throughput

0.479

High

837076

ZBT10
Zinc finger and BTB domain-containing protein 10

1

12

High-throughput

0.479

High

837077

MCRS1
Microspherule protein 1

1

4

High-throughput

0.479

High

837079

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

837080

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

837081

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

837083

PCGF1
Polycomb group RING finger protein 1

1

13

High-throughput

0.479

High

837085

PDIP3
Polymerase delta-interacting protein 3

1

1

High-throughput

0.479

High

837086

PCGF6
Polycomb group RING finger protein 6

1

19

High-throughput

0.479

High

837087

BRD8
Bromodomain-containing protein 8

1

20

High-throughput

0.479

High

837088

ING2
Inhibitor of growth protein 2

1

6

High-throughput

0.479

High

837090

ZN644
Zinc finger protein 644

1

10

High-throughput

0.479

High

837092

ARP5
Actin-related protein 5

1

10

High-throughput

0.479

High

837094

GRPE1
GrpE protein homolog 1, mitochondrial

1

7

High-throughput

0.479

High

837095

PRD16
Histone-lysine N-methyltransferase PRDM16

1

2

High-throughput

0.479

High

837097

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

837098

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

837100

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

14

High-throughput

0.479

High

837101

MO4L1
Mortality factor 4-like protein 1

1

3

High-throughput

0.479

High

837102

TRPS1
Zinc finger transcription factor Trps1

1

10

High-throughput

0.479

High

837103

DACH1
Dachshund homolog 1

1

2

High-throughput

0.479

High

837104

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

5

High-throughput

0.479

High

837105

ZHX1
Zinc fingers and homeoboxes protein 1

1

17

High-throughput

0.479

High

837107

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

837108

PHF8
Histone lysine demethylase PHF8

1

17

High-throughput

0.479

High

837109

SATB2
DNA-binding protein SATB2

1

7

High-throughput

0.479

High

837110

ZN148
Zinc finger protein 148

1

12

High-throughput

0.479

High

837111

ZN281
Zinc finger protein 281

1

12

High-throughput

0.479

High

837113

NCOR2
Nuclear receptor corepressor 2

1

13

High-throughput

0.479

High

837114

ZHX2
Zinc fingers and homeoboxes protein 2

1

12

High-throughput

0.479

High

837084

NUP58
Nucleoporin p58/p45

1

1

High-throughput

0.470

High

837093

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.458

High

837099

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.458

High

837023

HUTH
Histidine ammonia-lyase

1

1

High-throughput

0.457

High

837033

TPM4
Tropomyosin alpha-4 chain

1

2

High-throughput

0.457

High

837059

MYH14
Myosin-14

1

1

High-throughput

0.457

High

541874

TOP1
DNA topoisomerase 1

1

4

Small-scale

0.408

High

837096

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.316

High

837043

LSAMP
Limbic system-associated membrane protein

1

0

High-throughput

0.268

Low

837106

EPDR1
Mammalian ependymin-related protein 1

1

0

High-throughput

0.261

Low

837049

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025