HitPredict

Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 776 Hs			1 670
+	Hs
		1041127 CUL1_HUMAN (1-776): 0: 911: 100.00		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		571441 CUL1_HUMAN (1-776): 0: 911: 100.00		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		134026 CUL1_HUMAN (1-776): 0: 911: 100.00		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		1043613 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX18_HUMAN (1-670): 5.81e-174: 513: 100.00
+	Hs
		1042650 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX18_HUMAN (1-670): 5.81e-174: 513: 100.00
+	Mm
		1225206 CUL3_MOUSE (9-776): 0: 747: 30.35		DDX18_MOUSE (1-670): 1.34e-167: 496: 85.40
+	Hs
		571444 CUL4A_HUMAN (7-776): 0: 781: 30.41		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		1043492 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		571445 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		134029 CUL4B_HUMAN (7-776): 0: 773: 29.90		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		1042199 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		571443 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Mm
		1207268 CUL3_MOUSE (9-776): 0: 747: 30.35		Q8BTS0_MOUSE (69-600): 1.7e-133: 407: 22.39
+	Hs
		134028 CUL3_HUMAN (9-776): 0: 748: 30.47		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		1041422 CUL2_HUMAN (13-776): 0: 720: 35.98		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		571442 CUL2_HUMAN (13-776): 0: 720: 35.98		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		134027 CUL2_HUMAN (13-776): 0: 720: 35.98		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		571542 CUL5_HUMAN (2-776): 0: 622: 28.85		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		134152 CUL5_HUMAN (2-776): 0: 622: 28.85		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59