Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 22709582, 26100637, 26286618, 17254749, 35563538, 17192413, 21145461, 22911784, 19617556
Identification Methods affinity chromatography technology, enzymatic study, fluorescent resonance energy transfer, protein complementation assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~Cullin, Cullin~Cullin_Nedd8
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000209 - protein polyubiquitination
GO:0000922 - spindle pole
GO:0001831 - trophectodermal cellular morphogenesis
and 56 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 768
Hs

1 768
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+ Dm
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+ Ce
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024