HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: ABTB2 (Q8N961)
Ankyrin repeat and BTB/POZ domain-containing protein 2
Gene: ABTB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.80	0.721

Property	Details
Experiments	18429817, 36936774
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 1025
+	Hs
		1021397 CUL3_HUMAN (1-768): 0: 951: 100.00		ANK3_HUMAN (123-709): 4.58e-116: 397: 12.74
+	Hs
		1042221 CUL3_HUMAN (1-768): 0: 951: 100.00		ABTB1_HUMAN (572-988): 4.09e-62: 221: 17.90
+	Hs
		214258 CUL3_HUMAN (1-768): 0: 951: 100.00		SPOP_HUMAN (735-995): 1.87e-61: 216: 24.54
+	Hs
		1041712 CUL3_HUMAN (1-768): 0: 951: 100.00		KLH12_HUMAN (821-1024): 3.69e-58: 212: 21.46
+	Hs
		1041805 CUL3_HUMAN (1-768): 0: 951: 100.00		SPOPL_HUMAN (735-995): 1.67e-58: 208: 23.35
+	Hs
		1041853 CUL3_HUMAN (1-768): 0: 951: 100.00		KLH24_HUMAN (822-1024): 1.58e-55: 205: 20.19
+	Hs
		1042026 CUL3_HUMAN (1-768): 0: 951: 100.00		Q8N4I8_HUMAN (798-1023): 3.44e-58: 204: 16.02
+	Hs
		307170 CUL3_HUMAN (1-768): 0: 951: 100.00		KLHL2_HUMAN (822-1005): 7.41e-55: 203: 17.39
+	Hs
		1042324 CUL3_HUMAN (1-768): 0: 951: 100.00		KLHL5_HUMAN (803-1024): 1.38e-53: 202: 16.45
+	Hs
		166925 CUL3_HUMAN (1-768): 0: 951: 100.00		ANR28_HUMAN (82-531): 1.15e-52: 202: 9.66
+	Rn
		78189 CUL3_RAT (1-768): 0: 951: 99.61		KLH17_RAT (827-1024): 5.61e-54: 201: 18.72
+	Hs
		1041852 CUL3_HUMAN (1-768): 0: 951: 100.00		KLH17_HUMAN (827-1024): 4.18e-53: 199: 17.73
+	Hs
		1042054 CUL3_HUMAN (1-768): 0: 951: 100.00		ANR52_HUMAN (216-712): 1.03e-48: 190: 13.54
+	Hs
		1042070 CUL3_HUMAN (1-768): 0: 951: 100.00		RCBT1_HUMAN (825-991): 1.14e-47: 180: 25.15
+	Hs
		307251 CUL3_HUMAN (1-768): 0: 951: 100.00		RCBT2_HUMAN (808-991): 2.59e-45: 174: 23.91
+	Hs
		1042329 CUL3_HUMAN (1-768): 0: 951: 100.00		BTBD9_HUMAN (811-994): 4.06e-41: 163: 22.58
+	Hs
		1042057 CUL3_HUMAN (1-768): 0: 951: 100.00		KLH23_HUMAN (836-995): 3.73e-39: 156: 22.98
+	Hs
		556700 CUL3_HUMAN (1-768): 0: 951: 100.00		ANK1_HUMAN (512-1010): 1.97e-36: 152: 10.75
+	Hs
		1041986 CUL3_HUMAN (1-768): 0: 951: 100.00		KLHL7_HUMAN (837-1005): 1.36e-33: 139: 20.71
+	Hs
		64280 CUL3_HUMAN (1-768): 0: 951: 100.00		ABTB3_HUMAN (250-509): 1.97e-12: 73.8: 11.64