Protein: AINX
Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5)

Gene: AINX, INA
Organism: Homo sapiens
Interactions: 150
UniProt ID: Q16352

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005615 - extracellular space
GO:0005882 - intermediate filament
GO:0005883 - neurofilament
GO:0021762 - substantia nigra development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

474701

VIME
Vimentin

4

20

High-throughput

0.903

High

451393

NFM
Neurofilament medium polypeptide

3

20

High-throughput

0.861

High

570435

GFAP
Glial fibrillary acidic protein

3

19

High-throughput

0.861

High

437191

K2C8
Keratin, type II cytoskeletal 8

3

20

High-throughput

0.827

High

551616

NFH
Neurofilament heavy polypeptide

2

20

High-throughput

0.811

High

1157257

SYNCI
Syncoilin

2

20

High-throughput

0.811

High

436879

K1C18
Keratin, type I cytoskeletal 18

2

20

High-throughput

0.754

High

227229

KRT86
Keratin, type II cuticular Hb6

1

20

High-throughput

0.691

High

385116

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.691

High

475761

K2C7
Keratin, type II cytoskeletal 7

1

20

High-throughput

0.691

High

476323

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.691

High

606120

DESM
Desmin

1

20

High-throughput

0.691

High

777477

K22E
Keratin, type II cytoskeletal 2 epidermal

1

20

High-throughput

0.691

High

876593

NEST
Nestin

1

20

High-throughput

0.691

High

1108824

BFSP2
Phakinin

1

20

High-throughput

0.691

High

1127789

K1H2
Keratin, type I cuticular Ha2

1

20

High-throughput

0.691

High

1135570

K2C72
Keratin, type II cytoskeletal 72

1

20

High-throughput

0.691

High

1145952

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.691

High

1157221

K1C39
Keratin, type I cytoskeletal 39

1

20

High-throughput

0.691

High

1157226

K1C27
Keratin, type I cytoskeletal 27

1

20

High-throughput

0.691

High

1157230

K2C78
Keratin, type II cytoskeletal 78

1

20

High-throughput

0.691

High

1157252

K1C23
Keratin, type I cytoskeletal 23

1

20

High-throughput

0.691

High

345881

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

3

2

Small-scale

0.633

High

475583

K1C19
Keratin, type I cytoskeletal 19

1

20

High-throughput

0.618

High

833277

PERI
Peripherin

1

20

High-throughput

0.618

High

1157219

CC183
Coiled-coil domain-containing protein 183

3

13

High-throughput

0.609

High

1157242

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

3

1

High-throughput

0.609

High

1157254

GAN
Gigaxonin

3

16

High-throughput

0.609

High

1157259

ANM8
Protein arginine N-methyltransferase 8

3

9

High-throughput

0.609

High

791419

SYUA
Alpha-synuclein

2

3

High-throughput

0.601

High

457098

CAN1
Calpain-1 catalytic subunit

2

6

High-throughput

0.574

High

1157244

RSPRY
RING finger and SPRY domain-containing protein 1

2

7

High-throughput

0.574

High

1157247

CC120
Coiled-coil domain-containing protein 120

2

5

High-throughput

0.574

High

730614

1433S
14-3-3 protein sigma

1

20

High-throughput

0.554

High

1049329

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

899928

FXR1
RNA-binding protein FXR1

1

14

High-throughput

0.541

High

529875

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.536

High

575138

IDE
Insulin-degrading enzyme

1

11

High-throughput

0.536

High

691045

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

891580

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.536

High

1030645

ANK2
Ankyrin-2

1

12

High-throughput

0.536

High

1107757

SQSTM
Sequestosome-1

1

6

High-throughput

0.536

High

967758

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

4

Small-scale

0.533

High

177382

ARHGB
Rho guanine nucleotide exchange factor 11

2

17

High-throughput

0.521

High

1027959

ECT2L
Epithelial cell-transforming sequence 2 oncogene-like

2

18

High-throughput

0.521

High

1157220

CP135
Centrosomal protein of 135 kDa

2

14

High-throughput

0.521

High

1157229

CNTRB
Centrobin

2

6

High-throughput

0.521

High

1157261

RHG23
Rho GTPase-activating protein 23

2

10

High-throughput

0.521

High

1143132

PLEC
Plectin

1

20

High-throughput

0.515

High

422172

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.515

High

562728

BMP1
Bone morphogenetic protein 1

1

0

High-throughput

0.513

High

212027

M3K13
Mitogen-activated protein kinase kinase kinase 13

1

10

High-throughput

0.489

High

335463

SLU7
Pre-mRNA-splicing factor SLU7

1

1

High-throughput

0.489

High

471040

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

8

High-throughput

0.489

High

682495

S100P
Protein S100-P

1

3

High-throughput

0.489

High

719018

WEE1
Wee1-like protein kinase

1

19

High-throughput

0.489

High

788040

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

5

High-throughput

0.489

High

839157

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

3

High-throughput

0.489

High

882498

ARRB1
Beta-arrestin-1

1

3

High-throughput

0.489

High

966365

1433G
14-3-3 protein gamma

1

20

High-throughput

0.489

High

1085884

TWF1
Twinfilin-1

1

4

High-throughput

0.489

High

1097673

STK3
Serine/threonine-protein kinase 3

1

7

High-throughput

0.489

High

1124460

MAP7
Ensconsin

1

20

High-throughput

0.489

High

1143025

CDK10
Cyclin-dependent kinase 10

1

5

High-throughput

0.489

High

1157213

CF184
Cilia- and flagella-associated protein 184

1

2

High-throughput

0.489

High

1157223

CXB7
Gap junction beta-7 protein

1

7

High-throughput

0.489

High

1157225

CAN12
Calpain-12

1

4

High-throughput

0.489

High

1157228

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.489

High

1157232

KLH36
Kelch-like protein 36

1

3

High-throughput

0.489

High

1157233

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

16

High-throughput

0.489

High

1157236

TBCK
TBC domain-containing protein kinase-like protein

1

10

High-throughput

0.489

High

1157240

CDKL2
Cyclin-dependent kinase-like 2

1

6

High-throughput

0.489

High

1157246

CERS2
Ceramide synthase 2

1

3

High-throughput

0.489

High

1157262

PAK5
Serine/threonine-protein kinase PAK 5

1

11

High-throughput

0.489

High

1157265

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

1

8

High-throughput

0.489

High

1157266

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

3

High-throughput

0.489

High

1157269

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

17

High-throughput

0.489

High

582816

EZRI
Ezrin

1

2

High-throughput

0.479

High

904770

MECP2
Methyl-CpG-binding protein 2

1

9

High-throughput

0.479

High

971569

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.479

High

1157217

ODFP2
Outer dense fiber protein 2

1

11

High-throughput

0.479

High

1157245

BICD1
Protein bicaudal D homolog 1

1

20

High-throughput

0.479

High

1157258

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

936760

NP1L1
Nucleosome assembly protein 1-like 1

1

1

High-throughput

0.470

High

255043

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.457

High

1157267

ITM2B
Integral membrane protein 2B

1

12

High-throughput

0.445

High

106004

APRIO
Alternative prion protein

1

8

High-throughput

0.437

High

138132

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

11

High-throughput

0.437

High

157429

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.437

High

241800

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.437

High

260012

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.437

High

272217

OBSL1
Obscurin-like protein 1

1

13

High-throughput

0.437

High

297623

PIAS1
E3 SUMO-protein ligase PIAS1

1

7

High-throughput

0.437

High

315633

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.437

High

331003

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

372135

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.437

High

373950

RASN
GTPase NRas

1

4

High-throughput

0.437

High

375556

RASK
GTPase KRas

1

3

High-throughput

0.437

High

406226

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.437

High

411998

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

461522

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.437

High

474018

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.437

High

862175

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.437

High

942641

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

14

High-throughput

0.437

High

1023017

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

1

20

High-throughput

0.437

High

1086226

TFCP2
Alpha-globin transcription factor CP2

1

7

High-throughput

0.437

High

1103195

CTBP1
C-terminal-binding protein 1

1

6

High-throughput

0.437

High

1126913

RBM39
RNA-binding protein 39

1

5

High-throughput

0.437

High

1134917

CUL7
Cullin-7

1

4

High-throughput

0.437

High

1140331

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.437

High

1155408

EZH2
Histone-lysine N-methyltransferase EZH2

1

11

High-throughput

0.437

High

1157215

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

6

High-throughput

0.437

High

1157216

MIDN
Midnolin

1

3

High-throughput

0.437

High

1157224

SYNE3
Nesprin-3

1

9

High-throughput

0.437

High

1157227

ARHGJ
Rho guanine nucleotide exchange factor 19

1

18

High-throughput

0.437

High

1157231

NIN
Ninein

1

20

High-throughput

0.437

High

1157235

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.437

High

1157238

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

10

High-throughput

0.437

High

1157239

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.437

High

1157241

REQU
Zinc finger protein ubi-d4

1

19

High-throughput

0.437

High

1157243

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.437

High

1157251

ANM1
Protein arginine N-methyltransferase 1

1

9

High-throughput

0.437

High

1157253

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.437

High

1157255

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.437

High

1157256

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.437

High

1157260

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.437

High

1157263

ANFY1
Rabankyrin-5

1

12

High-throughput

0.437

High

1157264

XPO7
Exportin-7

1

8

High-throughput

0.437

High

1157268

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

213146

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

High-throughput

0.407

High

324137

CE152
Centrosomal protein of 152 kDa

1

4

High-throughput

0.407

High

429961

JUN
Transcription factor Jun

1

12

High-throughput

0.407

High

516665

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

2

High-throughput

0.407

High

626249

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

12

High-throughput

0.407

High

765554

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.407

High

838106

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

4

Small-scale

0.407

High

911603

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.407

High

934671

TERA
Transitional endoplasmic reticulum ATPase

1

9

High-throughput

0.407

High

1157218

CE170
Centrosomal protein of 170 kDa

1

10

High-throughput

0.407

High

1157234

POC5
Centrosomal protein POC5

1

2

High-throughput

0.407

High

1157248

CEP63
Centrosomal protein of 63 kDa

1

16

High-throughput

0.407

High

1157249

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.407

High

1157270

MB212
Protein mab-21-like 2

3

0

High-throughput

0.347

High

1157250

MIPEP
Mitochondrial intermediate peptidase

2

0

High-throughput

0.319

High

1028993

TIAR
Nucleolysin TIAR

1

0

High-throughput

0.279

Low

1157214

VWA3B
von Willebrand factor A domain-containing protein 3B

1

0

High-throughput

0.279

Low

573116

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.249

Low

1157222

CENPP
Centromere protein P

1

0

High-throughput

0.249

Low

1157212

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1157237

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025