HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1962
+	Hs
		1042852 CUL3_HUMAN (1-768): 0: 951: 100.00		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		1042585 CUL3_HUMAN (1-768): 0: 951: 100.00		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Hs
		1041284 CUL1_HUMAN (18-768): 0: 707: 30.57		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		1041505 CUL2_HUMAN (30-768): 0: 672: 26.17		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		1042196 CUL3_HUMAN (1-768): 0: 951: 100.00		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		1042076 CUL3_HUMAN (1-768): 0: 951: 100.00		KMT2C_HUMAN (1071-1765): 1.31e-13: 79.4: 10.54
+	Hs
		1042718 CUL3_HUMAN (1-768): 0: 951: 100.00		RRBP1_HUMAN (329-778): 2.37e-09: 65.1: 13.30
+	Hs
		998679 CUL3_HUMAN (1-768): 0: 951: 100.00		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		998680 CUL4B_HUMAN (5-768): 0: 779: 36.77		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		998678 CUL1_HUMAN (18-768): 0: 707: 30.57		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		1041404 CUL2_HUMAN (30-768): 0: 672: 26.17		ARI1B_HUMAN (551-1540): 1.58e-09: 65.5: 8.99