HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: AFG2B (Q9BVQ7)
ATPase family gene 2 protein homolog B (EC 3.6.4.10) (AFG2 AAA ATPase homolog B) (Ribosome biogenesis protein SPATA5L1) (Spermatogenesis-associated protein 5-like protein 1)
Gene: AFG2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 753
+	Hs
		874907 CUL3_HUMAN (1-768): 0: 951: 100.00		TERA_HUMAN (9-743): 0: 548: 33.42
+	Hs
		1042056 CUL3_HUMAN (1-768): 0: 951: 100.00		AFG2A_HUMAN (49-748): 7.41e-162: 492: 34.97
+	Hs
		177499 CUL3_HUMAN (1-768): 0: 951: 100.00		NVL_HUMAN (15-743): 5.5e-147: 453: 29.19
+	Hs
		874908 CUL4A_HUMAN (10-768): 0: 791: 38.32		TERA_HUMAN (9-743): 0: 548: 33.42
+	Hs
		874909 CUL4B_HUMAN (5-768): 0: 779: 36.77		TERA_HUMAN (9-743): 0: 548: 33.42
+	Hs
		1040745 CUL3_HUMAN (1-768): 0: 951: 100.00		PEX6_HUMAN (76-748): 2.61e-115: 373: 27.07
+	Hs
		218008 CUL3_HUMAN (1-768): 0: 951: 100.00		PEX1_HUMAN (10-711): 3.01e-110: 365: 23.85
+	Hs
		874905 CUL1_HUMAN (18-768): 0: 707: 30.57		TERA_HUMAN (9-743): 0: 548: 33.42
+	Hs
		874906 CUL2_HUMAN (30-768): 0: 672: 26.17		TERA_HUMAN (9-743): 0: 548: 33.42
+	Dm
		1097193 CUL1_DROME (29-768): 0: 669: 27.49		TERA_DROME (11-743): 0: 539: 30.26
+	Hs
		875192 CUL5_HUMAN (25-768): 0: 597: 23.77		TERA_HUMAN (9-743): 0: 548: 33.42
+	Sc
		636771 CDC53_YEAST (30-768): 0: 573: 22.08		CDC48_YEAST (22-500): 7e-78: 269: 23.81