HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: PATZ1 (Q9HBE1)
POZ-, AT hook-, and zinc finger-containing protein 1 (BTB/POZ domain zinc finger transcription factor) (Protein kinase A RI subunit alpha-associated protein) (Zinc finger and BTB domain-containing protein 19) (Zinc finger protein 278) (Zinc finger sarcoma gene protein)
Gene: PATZ1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 687
+	Hs
		1041826 CUL3_HUMAN (1-768): 0: 951: 100.00		Z585A_HUMAN (108-687): 0: 634: 17.46
+	Hs
		983757 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF91_HUMAN (65-629): 0: 582: 18.40
+	Hs
		1041954 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN227_HUMAN (74-632): 0: 565: 21.12
+	Hs
		1041738 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN569_HUMAN (91-573): 2.26e-176: 520: 18.22
+	Hs
		67426 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN850_HUMAN (222-687): 6.04e-171: 519: 21.67
+	Hs
		970659 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF45_HUMAN (74-574): 1.47e-167: 498: 18.91
+	Hs
		1041764 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN658_HUMAN (123-687): 1.12e-153: 473: 15.04
+	Hs
		549161 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN250_HUMAN (393-655): 6.02e-90: 293: 23.51
+	Hs
		880248 CUL3_HUMAN (1-768): 0: 951: 100.00		MAZ_HUMAN (350-503): 1.98e-70: 238: 70.13
+	Hs
		846676 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF84_HUMAN (48-319): 6.73e-57: 207: 9.68
+	Hs
		73009 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN879_HUMAN (190-406): 1.96e-57: 205: 18.37
+	Hs
		1041578 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN268_HUMAN (73-319): 3.13e-51: 193: 10.63
+	Hs
		565092 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF7_HUMAN (150-407): 2.65e-47: 179: 18.01
+	Hs
		1041579 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN234_HUMAN (61-256): 8.59e-26: 114: 6.63
+	Hs
		1041998 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN100_HUMAN (357-623): 1.79e-24: 110: 28.36
+	Hs
		73014 CUL3_HUMAN (1-768): 0: 951: 100.00		B4DU56_HUMAN (121-269): 2.5e-16: 84.9: 9.40
+	Hs
		1041728 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN805_HUMAN (180-333): 8.49e-16: 83.1: 12.23
+	Hs
		988832 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33B_HUMAN (8-215): 3.63e-15: 81.4: 9.09
+	Hs
		1041966 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN573_HUMAN (294-438): 4.23e-12: 71.2: 31.97
+	Hs
		1041543 CUL3_HUMAN (1-768): 0: 951: 100.00		VEZF1_HUMAN (413-519): 2.07e-11: 68.9: 34.51