HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: MALT1 (Q9UDY8)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase)
Gene: MALT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031398 - positive regulation of protein ubiquitination
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 824
+	Hs
		1042342 CUL3_HUMAN (1-768): 0: 951: 100.00		HMCN1_HUMAN (17-646): 2.53e-55: 210: 14.88
+	Hs
		313973 CUL3_HUMAN (1-768): 0: 951: 100.00		PPN_HUMAN (4-329): 8.04e-48: 186: 19.47
+	Hs
		1042187 CUL3_HUMAN (1-768): 0: 951: 100.00		PXDN_HUMAN (192-434): 6.42e-29: 126: 13.31
+	Hs
		609280 CUL4B_HUMAN (5-768): 0: 779: 36.77		FGFR3_HUMAN (4-585): 4.37e-84: 287: 14.33
+	Hs
		49984 CUL3_HUMAN (1-768): 0: 951: 100.00		PXDNL_HUMAN (165-361): 1.6e-20: 99.8: 17.12
+	Hs
		957538 CUL3_HUMAN (1-768): 0: 951: 100.00		PGBM_HUMAN (226-297): 5.93e-12: 72: 24.39
+	Hs
		1042166 CUL3_HUMAN (1-768): 0: 951: 100.00		TITIN_HUMAN (22-563): 7.83e-10: 65.3: 9.73
+	Hs
		957539 CUL4A_HUMAN (10-768): 0: 791: 38.32		PGBM_HUMAN (226-297): 5.93e-12: 72: 24.39
+	Hs
		1043127 CUL4A_HUMAN (10-768): 0: 791: 38.32		TITIN_HUMAN (22-563): 7.83e-10: 65.3: 9.73
+	Hs
		1043482 CUL4B_HUMAN (5-768): 0: 779: 36.77		TITIN_HUMAN (22-563): 7.83e-10: 65.3: 9.73
+	Hs
		1041413 CUL2_HUMAN (30-768): 0: 672: 26.17		TITIN_HUMAN (22-563): 7.83e-10: 65.3: 9.73