HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1281
+	Hs
		563252 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF12_HUMAN (748-1266): 3.84e-51: 195: 10.54
+	Hs
		73009 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN879_HUMAN (883-1266): 1.21e-51: 193: 10.57
+	Hs
		988826 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33A_HUMAN (925-1261): 1.35e-35: 148: 8.33
+	Hs
		1041579 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN234_HUMAN (949-1266): 8.94e-33: 138: 8.75
+	Hs
		983757 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF91_HUMAN (919-1261): 4.66e-31: 135: 9.84
+	Hs
		1043300 CUL4A_HUMAN (10-768): 0: 791: 38.32		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		1042693 CUL3_HUMAN (1-768): 0: 951: 100.00		RBAK_HUMAN (1017-1278): 9.63e-26: 116: 12.12
+	Hs
		1042724 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN624_HUMAN (1101-1278): 9.55e-25: 113: 14.75
+	Hs
		563806 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF30_HUMAN (1116-1266): 5.48e-15: 81.9: 14.74
+	Hs
		1042690 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN226_HUMAN (1148-1266): 6.11e-14: 78.8: 12.61
+	Hs
		1033636 CUL2_HUMAN (30-768): 0: 672: 26.17		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		563262 CUL3_HUMAN (1-768): 0: 951: 100.00		ZNF14_HUMAN (1162-1270): 1.74e-10: 67.2: 16.07
+	Hs
		988832 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN33B_HUMAN (657-1007): 4.82e-10: 66.1: 10.94
+	Hs
		1041738 CUL3_HUMAN (1-768): 0: 951: 100.00		ZN569_HUMAN (1206-1278): 1.45e-09: 64.5: 23.29
+	Hs
		798891 CUL4A_HUMAN (10-768): 0: 791: 38.32		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Hs
		798890 CUL2_HUMAN (30-768): 0: 672: 26.17		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Hs
		620345 CUL1_HUMAN (18-768): 0: 707: 30.57		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60