Protein: S47A1
Multidrug and toxin extrusion protein 1 (MATE-1) (hMATE-1) (Solute carrier family 47 member 1)

Gene: S47A1, SLC47A1
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q96FL8

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006855 - xenobiotic transmembrane transport
GO:0015101 - organic cation transmembrane transporter activity
GO:0015179 - L-amino acid transmembrane transporter activity
GO:0015234 - thiamine transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1192278

ZACN
Ligand-gated cation channel ZACN

3

3

High-throughput

0.667

High

1242899

S39A4
Zinc transporter ZIP4

3

1

High-throughput

0.667

High

1360195

5HT3C
5-hydroxytryptamine receptor 3C

3

2

High-throughput

0.667

High

1294755

LYPD6
Ly6/PLAUR domain-containing protein 6

3

0

High-throughput

0.638

High

761095

GBRA3
Gamma-aminobutyric acid receptor subunit alpha-3

2

2

High-throughput

0.628

High

855373

5HT3A
5-hydroxytryptamine receptor 3A

2

2

High-throughput

0.628

High

1197857

S39AC
Zinc transporter ZIP12

2

1

High-throughput

0.628

High

1390779

GPR21
Probable G-protein coupled receptor 21

2

1

High-throughput

0.628

High

1042774

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

1

High-throughput

0.611

High

60738

F234B
Protein FAM234B

2

0

High-throughput

0.602

High

142149

NPT3
Sodium-dependent phosphate transport protein 3

2

0

High-throughput

0.602

High

1057571

ACHD
Acetylcholine receptor subunit delta

2

0

High-throughput

0.602

High

1292691

TMPSC
Transmembrane protease serine 12

2

0

High-throughput

0.602

High

1390787

SG196
Protein O-mannose kinase

3

2

High-throughput

0.593

High

639399

5NTD
5'-nucleotidase

2

0

High-throughput

0.585

High

1390785

FXYD6
FXYD domain-containing ion transport regulator 6

2

0

High-throughput

0.580

High

1005550

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

2

2

High-throughput

0.558

High

269880

IGSF3
Immunoglobulin superfamily member 3

1

0

High-throughput

0.546

High

132640

UPK1A
Uroplakin-1a

1

1

High-throughput

0.536

High

183956

S22A2
Solute carrier family 22 member 2

1

2

High-throughput

0.536

High

688613

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

4

High-throughput

0.536

High

688678

NKG2C
NKG2-C type II integral membrane protein

1

4

High-throughput

0.536

High

800313

INGR2
Interferon gamma receptor 2

1

1

High-throughput

0.536

High

880184

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.536

High

1010513

EREP3
Protein ENTREP3

1

1

High-throughput

0.536

High

1032638

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

1

High-throughput

0.536

High

1059324

NKG2E
NKG2-E type II integral membrane protein

1

4

High-throughput

0.536

High

1254074

LRC55
Leucine-rich repeat-containing protein 55

1

1

High-throughput

0.536

High

1316345

AGRG5
Adhesion G-protein coupled receptor G5

1

1

High-throughput

0.536

High

1390793

CLC2D
C-type lectin domain family 2 member D

1

2

High-throughput

0.536

High

164954

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

0

High-throughput

0.513

High

349529

TSN15
Tetraspanin-15

1

0

High-throughput

0.513

High

378645

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.513

High

407203

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

845531

PI2R
Prostacyclin receptor

1

0

High-throughput

0.513

High

1195454

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

1216661

OR2G6
Olfactory receptor 2G6

1

0

High-throughput

0.513

High

1219323

ECM29
Proteasome adapter and scaffold protein ECM29

1

0

High-throughput

0.513

High

1253592

SO4C1
Solute carrier organic anion transporter family member 4C1

1

0

High-throughput

0.513

High

1281753

T179B
Transmembrane protein 179B

1

0

High-throughput

0.513

High

1390780

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

1390783

TM2D2
TM2 domain-containing protein 2

1

0

High-throughput

0.513

High

1390786

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1390788

NRN1
Neuritin

1

0

High-throughput

0.513

High

1390792

PDXL2
Podocalyxin-like protein 2

1

0

High-throughput

0.513

High

1390796

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.513

High

230719

NKG2F
NKG2-F type II integral membrane protein

1

3

High-throughput

0.489

High

1249105

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

870828

GLRB
Glycine receptor subunit beta

1

1

High-throughput

0.445

High

1125869

FZD2
Frizzled-2

1

2

High-throughput

0.445

High

1291757

S22AG
Solute carrier family 22 member 16

1

2

High-throughput

0.445

High

1390781

SMO
Protein smoothened

1

2

High-throughput

0.445

High

1390797

FZD1
Frizzled-1

1

2

High-throughput

0.445

High

710424

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.426

High

914466

EFNB2
Ephrin-B2

1

0

High-throughput

0.426

High

1135364

SLMAP
Sarcolemmal membrane-associated protein

1

0

High-throughput

0.426

High

1155253

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.426

High

1159168

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.426

High

1192957

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

0

High-throughput

0.426

High

1211494

FREM2
FRAS1-related extracellular matrix protein 2

1

0

High-throughput

0.426

High

1337024

T161B
Transmembrane protein 161B

1

0

High-throughput

0.426

High

1340223

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.426

High

1364450

ELMO1
Engulfment and cell motility protein 1

1

0

High-throughput

0.426

High

1390778

MIA2
Melanoma inhibitory activity protein 2

1

0

High-throughput

0.426

High

1390791

CNNM1
Metal transporter CNNM1

1

0

High-throughput

0.426

High

1390795

CNOT6
CCR4-NOT transcription complex subunit 6

1

0

High-throughput

0.426

High

1390799

AT8A1
Phospholipid-transporting ATPase IA

1

0

High-throughput

0.426

High

1390800

PLXD1
Plexin-D1

1

0

High-throughput

0.426

High

1390776

TECT2
Tectonic-2

3

0

High-throughput

0.345

High

219347

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.279

Low

1390777

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

464195

TPM2
Tropomyosin beta chain

1

0

High-throughput

0.269

Low

606149

DESM
Desmin

1

0

High-throughput

0.269

Low

137086

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

0

High-throughput

0.232

Low

244755

ZC3H1
Zinc finger C3H1 domain-containing protein

1

0

High-throughput

0.232

Low

519546

MYBB
Myb-related protein B

1

0

High-throughput

0.232

Low

1023008

FAM3A
Protein FAM3A

1

0

High-throughput

0.232

Low

1188013

GNPTA
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

1

0

High-throughput

0.232

Low

1217349

STRP1
Striatin-interacting protein 1

1

0

High-throughput

0.232

Low

1231775

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

0

High-throughput

0.232

Low

1390775

BSCL2
Seipin

1

0

High-throughput

0.232

Low

1390782

DCTN5
Dynactin subunit 5

1

0

High-throughput

0.232

Low

1390784

XPO4
Exportin-4

1

0

High-throughput

0.232

Low

1390789

MA1C1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC

1

0

High-throughput

0.232

Low

1390790

STRN4
Striatin-4

1

0

High-throughput

0.232

Low

1390794

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

0

High-throughput

0.232

Low

1390798

EXC6B
Exocyst complex component 6B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025