Protein: FACE1
CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog)

Gene: FACE1, ZMPSTE24
Organism: Homo sapiens
Interactions: 121
UniProt ID: O75844

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0001942 - hair follicle development
GO:0003007 - heart morphogenesis
GO:0003229 - ventricular cardiac muscle tissue development
GO:0003231 - cardiac ventricle development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276408

CP1A1
Cytochrome P450 1A1

3

1

High-throughput

0.667

High

276487

RNF26
E3 ubiquitin-protein ligase RNF26

3

0

High-throughput

0.638

High

276432

VMAT1
Chromaffin granule amine transporter

2

1

High-throughput

0.628

High

276417

FPPS
Farnesyl pyrophosphate synthase

2

0

High-throughput

0.602

High

276438

TNR17
Tumor necrosis factor receptor superfamily member 17

2

0

High-throughput

0.602

High

276439

VAC14
Protein VAC14 homolog

2

0

High-throughput

0.602

High

276399

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.586

High

276443

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.586

High

276437

IFM3
Interferon-induced transmembrane protein 3

2

0

Small-scale

0.585

High

276433

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

276404

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

Small-scale

0.545

High

276400

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.536

High

276500

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.536

High

123437

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.513

High

134647

NPT3
Sodium-dependent phosphate transport protein 3

1

0

High-throughput

0.513

High

214442

MYO1B
Unconventional myosin-Ib

1

0

High-throughput

0.513

High

276405

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.513

High

276412

NEP
Neprilysin

1

0

Small-scale

0.513

High

276419

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

0

High-throughput

0.513

High

276421

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

276423

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

0

High-throughput

0.513

High

276425

CALX
Calnexin

1

0

High-throughput

0.513

High

276428

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

276434

FGF12
Fibroblast growth factor 12

1

0

High-throughput

0.513

High

276436

AMPD2
AMP deaminase 2

1

0

High-throughput

0.513

High

276444

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.513

High

276448

ADCK5
Uncharacterized aarF domain-containing protein kinase 5

1

0

High-throughput

0.513

High

276450

TM196
Transmembrane protein 196

1

0

High-throughput

0.513

High

276453

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

276460

ANR46
Ankyrin repeat domain-containing protein 46

1

0

High-throughput

0.513

High

276465

NRM
Nurim

1

0

High-throughput

0.513

High

276475

OPTN
Optineurin

1

0

High-throughput

0.513

High

276477

PDLI5
PDZ and LIM domain protein 5

1

0

High-throughput

0.513

High

276480

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

0

High-throughput

0.513

High

276484

ABHEA
Protein ABHD14A

1

0

High-throughput

0.513

High

276501

COPZ2
Coatomer subunit zeta-2

1

0

High-throughput

0.513

High

276508

PRLD1
PRELI domain-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

276509

WASC3
WASH complex subunit 3

1

0

High-throughput

0.513

High

276420

H15
Histone H1.5

1

0

High-throughput

0.493

High

276489

O51V1
Olfactory receptor 51V1

1

0

High-throughput

0.493

High

276457

CXB7
Gap junction beta-7 protein

1

1

High-throughput

0.489

High

276486

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.479

High

276414

CP2C9
Cytochrome P450 2C9

1

1

High-throughput

0.479

High

276440

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

276462

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

276468

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.479

High

276470

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

163688

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

226082

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

276401

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

276406

GCR
Glucocorticoid receptor

1

0

Small-scale

0.458

High

276407

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

276409

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

276410

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

276424

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

276427

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

276430

EMD
Emerin

1

0

High-throughput

0.458

High

276431

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

276451

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

276458

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

276464

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

276471

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

276473

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

276474

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

276479

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

276488

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

276490

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

276495

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

276497

T106B
Transmembrane protein 106B

1

0

High-throughput

0.458

High

276499

CHMP5
Charged multivesicular body protein 5

1

0

High-throughput

0.458

High

276503

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

276418

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

276455

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

276466

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

276476

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

276445

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.426

High

276452

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

276441

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.328

High

276472

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

0

High-throughput

0.328

High

276481

GPR21
Probable G-protein coupled receptor 21

2

0

High-throughput

0.328

High

276507

STX8
Syntaxin-8

2

0

High-throughput

0.328

High

173792

DFB4A
Defensin beta 4A

2

0

High-throughput

0.319

High

276502

MARH4
E3 ubiquitin-protein ligase MARCHF4

2

0

High-throughput

0.318

High

276456

PMF1
Polyamine-modulated factor 1

2

0

High-throughput

0.305

High

200201

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

0

High-throughput

0.279

Low

276403

DNAL4
Dynein axonemal light chain 4

1

0

High-throughput

0.279

Low

276415

IL7
Interleukin-7

1

0

High-throughput

0.279

Low

276422

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.279

Low

276426

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.279

Low

276446

KRA61
Keratin-associated protein 6-1

1

0

High-throughput

0.279

Low

276447

KR194
Keratin-associated protein 19-4

1

0

High-throughput

0.279

Low

276449

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.279

Low

276461

TMPSC
Transmembrane protease serine 12

1

0

High-throughput

0.279

Low

276463

MYLK4
Myosin light chain kinase family member 4

1

0

High-throughput

0.279

Low

276467

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

0

High-throughput

0.279

Low

276478

TECTB
Beta-tectorin

1

0

High-throughput

0.279

Low

276482

F118B
Protein FAM118B

1

0

High-throughput

0.279

Low

276483

S39A3
Zinc transporter ZIP3

1

0

High-throughput

0.279

Low

276485

DUS23
Dual specificity protein phosphatase 23

1

0

High-throughput

0.279

Low

276491

CENPH
Centromere protein H

1

0

High-throughput

0.279

Low

276493

GSX1
GS homeobox 1

1

0

High-throughput

0.279

Low

276494

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.279

Low

276496

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

276504

MO4L1
Mortality factor 4-like protein 1

1

0

High-throughput

0.279

Low

276510

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.279

Low

276429

CDX1
Homeobox protein CDX-1

1

0

High-throughput

0.269

Low

276506

IL19
Interleukin-19

1

0

High-throughput

0.269

Low

59861

SMIP7
Protein SPMIP7

1

0

High-throughput

0.249

Low

204837

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

276402

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

276411

ISG15
Ubiquitin-like protein ISG15

1

0

High-throughput

0.249

Low

276413

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

276416

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.249

Low

276435

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

276442

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.249

Low

276454

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

276459

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

276469

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

276492

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

276498

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

276505

TRM7
tRNA

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024