HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: DCA12 (Q5T6F0)
DDB1- and CUL4-associated factor 12 (Centrosome-related protein TCC52) (Testis cancer centrosome-related protein) (WD repeat-containing protein 40A)
Gene: DCAF12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	31973889, 21145461
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 453
+	Hs
		1043408 CUL4B_HUMAN (1-913): 0: 1184: 100.00		DC122_HUMAN (7-453): 0: 745: 64.07
+	Hs
		1043041 CUL4A_HUMAN (161-913): 0: 955: 81.83		DCA12_HUMAN (1-453): 0: 815: 100.00
+	Hs
		1043048 CUL4A_HUMAN (161-913): 0: 955: 81.83		DC122_HUMAN (7-453): 0: 745: 64.07
+	Hs
		1041034 CUL1_HUMAN (213-913): 0: 778: 30.16		DCA12_HUMAN (1-453): 0: 815: 100.00
+	Dm
		1124378 Q5BI50_DROME (139-913): 0: 952: 64.01		DCA12_DROME (3-452): 0: 607: 39.65