HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: DTL (Q9NZJ0)
Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein)
Gene: DTL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 21628527, 16861906, 31155351, 33961781, 16949367, 23555860, 26496610, 31973889, 17041588, 24962565, 21145461
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 913
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024