HitPredict

Interactor 1: PTC1 (Q13635)
Protein patched homolog 1 (PTC) (PTC1)
Gene: PTCH1

Interactor 2: BT2A1 (Q7KYR7)
Butyrophilin subfamily 2 member A1
Gene: BTN2A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1447 Hs			1 527
+	Hs
		1261870 PTC2_HUMAN (42-1281): 0: 1016: 52.57		BT2A2_HUMAN (1-527): 1.24e-138: 412: 77.59
+	Hs
		167829 NPC1_HUMAN (59-1191): 0: 713: 19.74		TRI27_HUMAN (274-504): 4.72e-66: 224: 41.95
+	Hs
		1016005 SCAP_HUMAN (204-731): 2.22e-87: 314: 15.44		BT2A2_HUMAN (1-527): 1.24e-138: 412: 77.59
+	Hs
		373127 HMDH_HUMAN (422-734): 7.48e-46: 181: 13.42		BT2A1_HUMAN (1-527): 2.56e-149: 440: 100.00
+	Hs
		1015986 SCAP_HUMAN (204-731): 2.22e-87: 314: 15.44		BTNL8_HUMAN (28-508): 1.02e-96: 304: 32.44
+	Hs
		1108436 PTHD3_HUMAN (337-744): 5.11e-51: 198: 18.25		BT2A2_HUMAN (1-527): 1.24e-138: 412: 77.59
+	Hs
		373125 HMDH_HUMAN (422-734): 7.48e-46: 181: 13.42		BTNL3_HUMAN (13-505): 4.9e-98: 306: 34.27