HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: RAB2A (P53994)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	27507650, 28706196, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 212
+	Mm
		104492 SYGP1_MOUSE (1-1340): 0: 1071: 100.00		RAB1A_MOUSE (3-212): 1.16e-85: 253: 45.24
+	Hs
		981344 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		RAB1A_HUMAN (3-212): 1.16e-85: 253: 45.24
+	Hs
		958001 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		RAB14_HUMAN (3-211): 1.87e-84: 250: 59.33
+	Hs
		976494 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		RB11A_HUMAN (3-212): 1.45e-83: 248: 46.67
+	Hs
		956227 SYGP1_HUMAN (1-1340): 0: 1060: 98.59		RAB4B_HUMAN (3-188): 5.18e-71: 216: 55.91
+	Hs
		956219 DAB2P_HUMAN (97-1339): 0: 858: 47.63		RAB4B_HUMAN (3-188): 5.18e-71: 216: 55.91
+	Hs
		956536 NGAP_HUMAN (84-1338): 0: 796: 43.40		RAB2A_HUMAN (1-212): 3.32e-89: 262: 98.59
+	Hs
		976645 NGAP_HUMAN (84-1338): 0: 796: 43.40		RB11A_HUMAN (3-212): 1.45e-83: 248: 46.67
+	Mm
		1243504 GAPD1_MOUSE (412-1068): 7.51e-131: 440: 13.18		RAB4B_MOUSE (3-188): 3.9e-71: 217: 55.91
+	Hs
		862772 IQGA1_HUMAN (232-723): 2.63e-106: 373: 14.29		RAB2A_HUMAN (1-212): 3.32e-89: 262: 98.59