Interactor 1: RUNX3 (Q13761)
Runt-related transcription factor 3 (Acute myeloid leukemia 2 protein) (Core-binding factor subunit alpha-3) (CBF-alpha-3) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEA2-alpha C) (PEBP2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit)
Gene: RUNX3
Interactor 2: PEBB (Q13951)
Core-binding factor subunit beta (CBF-beta) (Polyomavirus enhancer-binding protein 2 beta subunit) (PEA2-beta) (PEBP2-beta) (SL3-3 enhancer factor 1 subunit beta) (SL3/AKV core-binding factor beta subunit)
Gene: CBFB
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 1.00 | 0.942 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23333304, 31253590, 33961781, 32296183, 15138260, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CBF_beta~Runt |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0016513 - core-binding factor complex GO:0043371 - negative regulation of CD4-positive, alpha-beta T cell differentiation and 1 others more... |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
