HitPredict

Interactor 1: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Interactor 2: SDCG8 (Q86SQ7)
Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP)
Gene: SDCCAG8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27224062
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2472 Hs			1 713
+	Hs
		148786 SPTN1_HUMAN (1-2472): 0: 714: 100.00		CTRO_HUMAN (117-697): 1.46e-14: 79.9: 19.15
+	Hs
		724817 SPTN1_HUMAN (1-2472): 0: 714: 100.00		MYH9_HUMAN (333-707): 4.69e-13: 75.1: 13.25
+	Hs
		1045471 SPTN1_HUMAN (1-2472): 0: 714: 100.00		MY18A_HUMAN (233-700): 1.81e-10: 66.8: 16.84
+	Hs
		522612 SPTN1_HUMAN (1-2472): 0: 714: 100.00		MYH7_HUMAN (3-370): 1.85e-10: 66.6: 12.04
+	Hs
		1045418 SPTN1_HUMAN (1-2472): 0: 714: 100.00		PLEC_HUMAN (122-704): 8.8e-09: 61.4: 15.46
+	Mm
		93541 SPTA1_MOUSE (1-2472): 2.17e-161: 558: 54.20		DESP_MOUSE (6-575): 9.06e-17: 87.3: 12.67
+	Hs
		360644 SPTA1_HUMAN (1-2472): 2.98e-159: 552: 54.81		PLEC_HUMAN (122-704): 8.8e-09: 61.4: 15.46
+	Hs
		963361 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		SDCG8_HUMAN (1-713): 1.5e-53: 198: 100.00
+	Hs
		148142 SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41		CTRO_HUMAN (117-697): 1.46e-14: 79.9: 19.15
+	Hs
		164575 SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41		MYH9_HUMAN (333-707): 4.69e-13: 75.1: 13.25
+	Hs
		164647 SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41		MY18A_HUMAN (233-700): 1.81e-10: 66.8: 16.84
+	Hs
		148690 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		CTRO_HUMAN (117-697): 1.46e-14: 79.9: 19.15
+	Hs
		724781 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		MYH9_HUMAN (333-707): 4.69e-13: 75.1: 13.25
+	Mm
		93578 PLEC_MOUSE (1-1250): 7.03e-38: 159: 10.80		DESP_MOUSE (6-575): 9.06e-17: 87.3: 12.67
+	Hs
		963381 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		MY18A_HUMAN (233-700): 1.81e-10: 66.8: 16.84
+	Hs
		724786 DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59		MYH9_HUMAN (333-707): 4.69e-13: 75.1: 13.25
+	Hs
		974117 DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59		MY18A_HUMAN (233-700): 1.81e-10: 66.8: 16.84
+	Hs
		148841 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		CTRO_HUMAN (117-697): 1.46e-14: 79.9: 19.15
+	Hs
		724839 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		MYH9_HUMAN (333-707): 4.69e-13: 75.1: 13.25
+	Hs
		1068536 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		PLEC_HUMAN (122-704): 8.8e-09: 61.4: 15.46