HitPredict

Interactor 1: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	27248496, 31353912
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2472 Hs			1 626
+	Hs
		903212 SPTN1_HUMAN (1-2472): 0: 714: 100.00		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		963419 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		1068668 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		1068625 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		903137 SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		1281478 MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		903233 GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		903240 PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		903607 MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		197084 CP250_HUMAN (1768-2439): 4.39e-10: 67.7: 8.94		PRP4_HUMAN (401-624): 5.45e-40: 155: 15.09
+	Hs
		997881 CP250_HUMAN (1768-2439): 4.39e-10: 67.7: 8.94		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55