HitPredict

Interactor 1: BACD2 (Q13829)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial)
Gene: TNFAIP1

Interactor 2: CAN7 (Q9Y6W3)
Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH)
Gene: CAPN7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.654

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 316 Hs			1 813
+	Hs
		1045924 BACD2_HUMAN (1-316): 1.75e-146: 416: 100.00		Q7Z479_HUMAN (1-813): 0: 1127: 99.63
+	Hs
		1297996 KCTD7_HUMAN (2-123): 7.34e-39: 140: 34.40		CAN7_HUMAN (1-813): 0: 1126: 100.00
+	Mm
		139005 BACD1_MOUSE (2-316): 2.32e-119: 348: 61.44		CAN2_MOUSE (197-682): 0: 590: 20.19
+	Hs
		569002 KCTD7_HUMAN (2-123): 7.34e-39: 140: 34.40		CAN2_HUMAN (197-682): 0: 592: 20.76
+	Hs
		427919 KCTD7_HUMAN (2-123): 7.34e-39: 140: 34.40		CAN1_HUMAN (197-691): 0: 570: 20.34
+	Hs
		180619 KCTD7_HUMAN (2-123): 7.34e-39: 140: 34.40		CAN5_HUMAN (201-710): 0: 546: 21.72
+	Hs
		1297992 KCTD7_HUMAN (2-123): 7.34e-39: 140: 34.40		CAN10_HUMAN (230-801): 8.69e-174: 518: 20.33
+	Hs
		275506 KCTD7_HUMAN (2-123): 7.34e-39: 140: 34.40		CAN15_HUMAN (145-693): 2.06e-161: 499: 19.09
+	Hs
		1154464 KCTD7_HUMAN (2-123): 7.34e-39: 140: 34.40		CAN13_HUMAN (196-672): 8.09e-139: 428: 20.48