Interactor 1: TF2H2 (Q13888)
General transcription factor IIH subunit 2 (Basic transcription factor 2 44 kDa subunit) (BTF2 p44) (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit)
Gene: GTF2H2

Interactor 2: TF2H3 (Q13889)
General transcription factor IIH subunit 3 (Basic transcription factor 2 34 kDa subunit) (BTF2 p34) (General transcription factor IIH polypeptide 3) (TFIIH basal transcription factor complex p34 subunit)
Gene: GTF2H3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 28514442, 24981860, 33961781, 21157430, 15790571, 12080057, 26340423, 28977422, 8652557
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_4~Tfb4, Ssl1~Tfb4
Common GO terms GO:0000438 - core TFIIH complex portion of holo TFIIH complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 395
Hs

1 308
+ Hs
+ Mm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024