HitPredict

Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: AKAP9 (Q99996)
A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)
Gene: AKAP9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0086091 - regulation of heart rate by cardiac conduction
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 2221 Hs			1 3907
+	Hs
		1047242 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		CP250_HUMAN (2-1330): 1.53e-46: 189: 10.71
+	Hs
		1047186 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		MY18A_HUMAN (2166-2833): 7.07e-15: 84.3: 15.67
+	Hs
		1047120 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		CROCC_HUMAN (2982-3735): 2.21e-11: 72.8: 11.52
+	Hs
		317247 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PCNT_HUMAN (220-863): 6.95e-11: 71.2: 11.28
+	Hs
		551701 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		DESP_HUMAN (2135-3311): 1.98e-09: 66.5: 13.94
+	Rn
		1144096 SCNAA_RAT (1228-1710): 8.7e-21: 102: 12.66		MYH10_RAT (319-1141): 1.66e-19: 99.7: 16.46
+	Rn
		139218 SCN9A_RAT (1223-1736): 1.65e-19: 98.9: 12.70		MYH10_RAT (319-1141): 1.66e-19: 99.7: 16.46
+	Rn
		388058 SCN2A_RAT (1221-1548): 9.02e-17: 89.6: 15.94		MYH10_RAT (319-1141): 1.66e-19: 99.7: 16.46
+	Rn
		435888 SCN3A_RAT (1221-1548): 5.96e-15: 83.8: 15.68		MYH10_RAT (319-1141): 1.66e-19: 99.7: 16.46
+	Rn
		1144033 SCNAA_RAT (1228-1710): 8.7e-21: 102: 12.66		MYH9_RAT (2369-3442): 8.49e-11: 70.8: 14.16
+	Rn
		139217 SCN9A_RAT (1223-1736): 1.65e-19: 98.9: 12.70		MYH9_RAT (2369-3442): 8.49e-11: 70.8: 14.16
+	Mm
		69869 SCN2A_MOUSE (1221-1548): 1.89e-17: 91.9: 16.20		MYH9_MOUSE (2537-3497): 3.94e-09: 65.4: 14.72
+	Rn
		435886 SCN3A_RAT (1221-1548): 5.96e-15: 83.8: 15.68		MYH9_RAT (2369-3442): 8.49e-11: 70.8: 14.16