Protein: COMD1
COMM domain-containing protein 1 (Protein Murr1)

Gene: COMD1, COMMD1
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q8N668

Gene Ontology (top 5):
GO:0005507 - copper ion binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257145

CCD22
Coiled-coil domain-containing protein 22

9

1

Small-scale

0.976

High

1328853

COMD3
COMM domain-containing protein 3

7

1

Small-scale

0.965

High

1278350

COMD6
COMM domain-containing protein 6

10

0

Small-scale

0.932

High

1328857

COMDA
COMM domain-containing protein 10

5

6

Small-scale

0.927

High

1328845

COMD4
COMM domain-containing protein 4

8

0

Small-scale

0.917

High

1328849

COMD8
COMM domain-containing protein 8

7

0

Small-scale

0.911

High

1201135

CCD93
Coiled-coil domain-containing protein 93

6

0

Small-scale

0.906

High

1291788

COMD7
COMM domain-containing protein 7

6

0

Small-scale

0.898

High

1293486

COMD2
COMM domain-containing protein 2

6

0

Small-scale

0.896

High

1328844

COMD5
COMM domain-containing protein 5

5

0

Small-scale

0.880

High

1328850

COMD9
COMM domain-containing protein 9

4

0

High-throughput

0.853

High

1045521

TF65
Transcription factor p65

8

4

Small-scale

0.749

High

1277142

VP35L
VPS35 endosomal protein-sorting factor-like

5

1

Small-scale

0.720

High

1112916

CUL2
Cullin-2

4

5

Small-scale

0.713

High

683486

IKBA
NF-kappa-B inhibitor alpha

4

2

Small-scale

0.694

High

1328832

DEN10
DENN domain-containing protein 10

5

0

High-throughput

0.684

High

1328854

VPS29
Vacuolar protein sorting-associated protein 29

5

0

High-throughput

0.684

High

775770

ATP7B
Copper-transporting ATPase 2

3

1

Small-scale

0.678

High

1122848

TFDP1
Transcription factor Dp-1

3

1

High-throughput

0.675

High

1112599

CUL1
Cullin-1

3

5

Small-scale

0.670

High

171089

VP26C
Vacuolar protein sorting-associated protein 26C

4

0

High-throughput

0.667

High

282751

E2F6
Transcription factor E2F6

3

0

High-throughput

0.646

High

789172

NUP62
Nuclear pore glycoprotein p62

3

0

High-throughput

0.634

High

1328830

COMD1
COMM domain-containing protein 1

1

0

Small-scale

0.631

High

1022748

XIAP
E3 ubiquitin-protein ligase XIAP

2

2

Small-scale

0.618

High

193291

SOCS1
Suppressor of cytokine signaling 1

2

0

Small-scale

0.607

High

687266

HMGB2
High mobility group protein B2

2

1

Small-scale

0.603

High

540051

BCR
Breakpoint cluster region protein

2

0

High-throughput

0.602

High

1119582

NFYC
Nuclear transcription factor Y subunit gamma

2

0

High-throughput

0.602

High

1181008

TR16L
Tripartite motif-containing protein 16-like protein

2

0

High-throughput

0.602

High

1323490

S11IP
Serine/threonine-protein kinase 11-interacting protein

2

0

High-throughput

0.602

High

1326629

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.602

High

1328846

VP33B
Vacuolar protein sorting-associated protein 33B

2

0

High-throughput

0.602

High

1328855

TTF2
Transcription termination factor 2

2

0

High-throughput

0.602

High

728335

AKT1
RAC-alpha serine/threonine-protein kinase

2

1

Small-scale

0.600

High

902354

SCNND
Epithelial sodium channel subunit delta

2

2

Small-scale

0.599

High

1114940

CUL4A
Cullin-4A

2

5

Small-scale

0.595

High

533716

CLUS
Clusterin

2

0

Small-scale

0.593

High

1315308

TCAL8
Transcription elongation factor A protein-like 8

2

0

High-throughput

0.580

High

1328836

UPP
Uracil phosphoribosyltransferase homolog

2

0

High-throughput

0.580

High

1147066

ELOC
Elongin-C

2

0

Small-scale

0.577

High

1328858

R4GMX3
Polycomb complex protein BMI-1

1

2

High-throughput

0.575

High

361303

SODC
Superoxide dismutase [Cu-Zn]

2

0

Small-scale

0.569

High

1113694

CUL3
Cullin-3

1

5

Small-scale

0.561

High

1328833

KAT2A
Histone acetyltransferase KAT2A

1

1

Small-scale

0.561

High

1161326

HIF1A
Hypoxia-inducible factor 1-alpha

2

0

Small-scale

0.559

High

1048914

REL
Proto-oncogene c-Rel

1

4

Small-scale

0.554

High

799294

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.552

High

902324

SCNNB
Epithelial sodium channel subunit beta

2

2

Small-scale

0.549

High

1328842

SCLT1
Sodium channel and clathrin linker 1

2

0

High-throughput

0.547

High

370087

CYTS
Cystatin-S

1

2

High-throughput

0.536

High

370214

CYTN
Cystatin-SN

1

2

High-throughput

0.536

High

479936

CYTT
Cystatin-SA

1

2

High-throughput

0.536

High

626285

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

5

Small-scale

0.536

High

1026743

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

5

Small-scale

0.536

High

1030011

RELB
Transcription factor RelB

1

4

Small-scale

0.536

High

1065301

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1122888

TFDP2
Transcription factor Dp-2

1

1

High-throughput

0.536

High

1328852

CRNN
Cornulin

1

1

High-throughput

0.536

High

352779

F107A
Actin-associated protein FAM107A

1

0

Small-scale

0.529

High

385967

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

Small-scale

0.529

High

842803

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

0

Small-scale

0.529

High

1087458

GRSF1
G-rich sequence factor 1

1

0

Small-scale

0.529

High

1328843

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.529

High

943487

DSCR6
Protein ripply3

1

0

High-throughput

0.518

High

902340

SCNNG
Epithelial sodium channel subunit gamma

1

2

Small-scale

0.515

High

1107018

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

Small-scale

0.515

High

175731

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.513

High

207594

DHX15
ATP-dependent RNA helicase DHX15

1

0

High-throughput

0.513

High

238563

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.513

High

247140

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.513

High

343414

SNP29
Synaptosomal-associated protein 29

1

0

High-throughput

0.513

High

542797

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.513

High

843768

HD
Huntingtin

1

0

High-throughput

0.513

High

925951

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

1099436

SRSF6
Serine/arginine-rich splicing factor 6

1

0

High-throughput

0.513

High

1180464

C19L2
CWF19-like protein 2

1

0

High-throughput

0.513

High

1243423

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.513

High

1252025

TRI72
Tripartite motif-containing protein 72

1

0

High-throughput

0.513

High

1311691

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.513

High

1328835

STMN2
Stathmin-2

1

0

High-throughput

0.513

High

1328837

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

1328838

SPF45
Splicing factor 45

1

0

High-throughput

0.513

High

1328839

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.513

High

1328848

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

1328856

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.513

High

1115299

CUL4B
Cullin-4B

1

5

Small-scale

0.501

High

1328834

CUL5
Cullin-5

1

5

Small-scale

0.501

High

242281

PRKN
E3 ubiquitin-protein ligase parkin

1

0

Small-scale

0.480

High

1134986

CUL7
Cullin-7

1

0

Small-scale

0.480

High

122964

SGK1
Serine/threonine-protein kinase Sgk1

1

1

Small-scale

0.479

High

765705

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

1047231

ATP7A
Copper-transporting ATPase 1

1

1

Small-scale

0.479

High

1093796

BIRC1
Baculoviral IAP repeat-containing protein 1

1

2

Small-scale

0.479

High

822758

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

892699

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

508277

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

564058

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

Small-scale

0.458

High

761762

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

934858

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1067506

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.458

High

1328847

NMRL1
NmrA-like family domain-containing protein 1

1

0

Small-scale

0.458

High

445026

S10A9
Protein S100-A9

1

1

Small-scale

0.457

High

1103272

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

379673

IGHA1
Immunoglobulin heavy constant alpha 1

1

1

High-throughput

0.407

High

379754

IGHA2
Immunoglobulin heavy constant alpha 2

1

1

High-throughput

0.407

High

1212146

ATD3C
ATPase family AAA domain-containing protein 3C

2

0

High-throughput

0.328

High

1328840

F167A
Protein FAM167A

2

0

High-throughput

0.328

High

1328851

BAHC1
BAH and coiled-coil domain-containing protein 1

1

0

High-throughput

0.282

High

379014

PIGR
Polymeric immunoglobulin receptor

1

0

High-throughput

0.279

Low

963204

LYSC
Lysozyme C

1

0

High-throughput

0.279

Low

1179817

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1242796

LEG1H
Protein LEG1 homolog

1

0

High-throughput

0.279

Low

1308500

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.279

Low

1328831

O13G1
Olfactory receptor 13G1

1

0

High-throughput

0.279

Low

1328841

ODAD1
Outer dynein arm-docking complex subunit 1

1

0

High-throughput

0.279

Low

933440

S12A2
Solute carrier family 12 member 2

1

0

Small-scale

0.275

Low

522281

OSTP
Osteopontin

1

0

Small-scale

0.251

Low

1135493

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

517243

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025