Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: CABP1 (Q9NZU7)
Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin)
Gene: CABP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 15140941, 21134641
Identification Methods pull down, affinity chromatography technology, isothermal titration calorimetry, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ca_chan_IQ~EF-hand_7, EF-hand_7~Ion_trans
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 2221
Hs

1 370
+ Hs
+ Ce
+ Hs
+ Hs
+ Rn
+ Hs

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Last updated: 15 Jul 2024